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The role of the brain-derived neurotrophic factor genotype and parenting in early life in predicting externalizing and internalizing symptoms in children with attention-deficit hyperactivity disorder

DC Field Value Language
dc.contributor.authorPark, Subin-
dc.contributor.authorKim, Bung-Nyun-
dc.contributor.authorKim, Jae-Won-
dc.contributor.authorJung, Yeon-Kyung-
dc.contributor.authorLee, Jin-
dc.contributor.authorShin, Min-Sup-
dc.contributor.authorYoo, Hee Jeong-
dc.contributor.authorCho, Soo-Churl-
dc.date.accessioned2017-03-17T07:21:34Z-
dc.date.available2017-03-17T17:32:36Z-
dc.date.issued2014-11-25-
dc.identifier.citationBehavioral and Brain Functions, 10(1):43ko_KR
dc.identifier.urihttps://hdl.handle.net/10371/109810-
dc.description.abstractBackground
We aimed to determine whether early parenting is associated with externalizing and internalizing symptoms in children with attention-deficit hyperactivity disorder (ADHD) and whether such an association is affected by the brain-derived neurotrophic factor (BDNF) val66met polymorphism.

Methods
The participants included 92 patients with ADHD aged 6–15 years. Measures of parenting in early life and externalizing and internalizing symptoms and the genotype of the BDNF Val66Met polymorphism were obtained.

Results
The degree to which the babys autonomy was allowed was significantly and negatively correlated with the CDI scores in ADHD children (r = −0.38, p = 0.005). After adjusting for the childs gender, the childs age, the familys gross annual income, and the maternal education level, there was a significant interaction for the BDNF genotype and mothers positive feelings about caring in relation to the development of childhood anxiety/depression in ADHD children (F = 2.51, p = 0.011).

Conclusions
Our results provide evidence of an interaction between the BDNF met allele and early parenting on the development of depression/anxiety symptoms.
ko_KR
dc.language.isoenko_KR
dc.publisherBioMed Centralko_KR
dc.subjectBDNFko_KR
dc.subjectParentingko_KR
dc.subjectADHDko_KR
dc.titleThe role of the brain-derived neurotrophic factor genotype and parenting in early life in predicting externalizing and internalizing symptoms in children with attention-deficit hyperactivity disorderko_KR
dc.typeArticleko_KR
dc.contributor.AlternativeAuthor박수빈-
dc.contributor.AlternativeAuthor김붕년-
dc.contributor.AlternativeAuthor김재원-
dc.contributor.AlternativeAuthor정연경-
dc.contributor.AlternativeAuthor이진-
dc.contributor.AlternativeAuthor신민섭-
dc.contributor.AlternativeAuthor유희정-
dc.contributor.AlternativeAuthor조수철-
dc.identifier.doi10.1186/1744-9081-10-43-
dc.language.rfc3066en-
dc.rights.holderPark et al.; licensee BioMed Central Ltd.-
dc.date.updated2017-01-06T10:33:59Z-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Psychiatry (정신과학전공)Journal Papers (저널논문_정신과학전공)
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