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Detection of liver metastases: gadobenate dimeglumine-enhanced three-dimensional dynamic phases and one-hour delayed phase MR imaging versus superparamagnetic iron oxide-enhanced MR imaging

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dc.contributor.authorKim, Young Kon-
dc.contributor.authorLee, Jeong Min-
dc.contributor.authorKim, Chong Soo-
dc.contributor.authorChung, Gyung Ho-
dc.contributor.authorKim, Chan Young-
dc.contributor.authorKim, In Hee-
dc.date.accessioned2009-11-04-
dc.date.available2009-11-04-
dc.date.issued2005-
dc.identifier.citationEur Radiol 15:220–228en
dc.identifier.issn0938-7994 (Print)-
dc.identifier.issn1432-1084 (Electronic)-
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15624108-
dc.identifier.urihttp://hdl.handle.net/10371/11067-
dc.description.abstractThe aim of this study was to compare the diagnostic performance of gadobenate dimeglumine (Gd-BOPTA)-enhanced MR imaging, including dynamic phases and one-hour delayed phase, versus superparamagnetic iron oxide (SPIO)-enhanced imaging for detection of liver metastases. Twenty-three patients with 59 liver metastases underwent Gd-BOPTA-enhanced MR imaging (unenhanced, arterial, portal, equilibrium and one-hour delayed phase) using three-dimensional volumetric interpolated imaging and SPIO-enhanced T2-weighted turbo spin-echo and T2*-weighted gradient-echo sequences on a 1.5-T unit. Three observers independently interpreted the three sets of images, i.e. Gd-BOPTA-enhanced dynamic MRI (set 1), delayed phase imaging (set 2) and SPIO-enhanced MRI (set 3). Diagnostic accuracy was evaluated using the alternative-free response receiver operating chracteristic (ROC) analysis. Sensitivity and positive predictive value were also evaluated. The mean accuracy (Az values) and sensitivity of Gd-BOPTA-enhanced delayed phase imaging (0.982, 95.5%) were comparable to those of SPIO-enhanced imaging (0.984, 97.2%). In addition, Az values and sensitivities of both imaging sets were significantly higher than those of Gd-BOPTA-enhanced dynamic images (0.826, 77.4%: p<0.05). There was no significant difference in the positive predictive value among the three image sets. Gd-BOPTA-enhanced delayed phase imaging showed comparable diagnostic performance to SPIO-enhanced imaging for the detection of liver metastases, and had a better diagnostic performance than Gd-BOPTA-enhanced dynamic images.en
dc.language.isoenen
dc.publisherSpringer Verlagen
dc.subjectLiveren
dc.subjectNeoplasmen
dc.subjectMagnetic resonance imagingen
dc.subjectContrast agentsen
dc.titleDetection of liver metastases: gadobenate dimeglumine-enhanced three-dimensional dynamic phases and one-hour delayed phase MR imaging versus superparamagnetic iron oxide-enhanced MR imagingen
dc.typeArticleen
dc.contributor.AlternativeAuthor김영곤-
dc.contributor.AlternativeAuthor이정민-
dc.contributor.AlternativeAuthor김종수-
dc.contributor.AlternativeAuthor정경호-
dc.contributor.AlternativeAuthor김찬영-
dc.contributor.AlternativeAuthor김인희-
dc.identifier.doi10.1007/s00330-004-2570-3-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Radiology (영상의학전공)Journal Papers (저널논문_영상의학전공)
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