S-Space College of Medicine/School of Medicine (의과대학/대학원) Biomedical Engineering (의공학전공) Journal Papers (저널논문_의공학전공)
Electrochemical nanoneedle biosensor based on multiwall carbon nanotube
- Boo, Hankil; Jeong, Ran-A; Park, Sejin; Kim, Keun Soo; An, Kay Hyeok; Lee, Young Hee; Han, Ji Hyung; Kim, Hee Chan; Chung, Taek Dong
- Issue Date
- American Chemical Society
- Anal Chem. 2006 Jan 15;78(2):617-20.
- Biosensing Techniques/instrumentation/*methods; Dopamine/*analysis; Glutamic Acid/*analysis; Microscopy, Electron, Scanning; Nanotubes, Carbon/*chemistry; Potentiometry
- We report the fabrication and analytical functions of a biosensor based on a nanoneedle consisting of a multiwall carbon nanotube attached to the end of an etched tungsten tip. The devised electrode is the smallest needle-type biosensor reported to date. The nanoneedles prepared in this work are 30 nm in diameter and 2-3 microm in length. Dopamine and glutamate, which are physiologically important neurotransmitters, were successfully detected using these nanoneedles. Bare nanoneedles detected dopamine in the range from 100 to 1000 microM by differential pulse voltammetry, and enzyme-modified nanoneedles were able to respond to glutamate in the 100-500 microM range by potentiostatic amperometry.
- 0003-2700 (Print)
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