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The effect of using blood culture bottle of bronchoalveolar larvage fluid in pneumonia : 27266871
Cited 1 time in
Web of Science
Cited 3 time in Scopus
- Authors
- Issue Date
- 2016-06-06
- Publisher
- BIOMED CENTRAL LTD
- Citation
- BMC INFECTIOUS DISEASES Vol.16, pp. 247
- Keywords
- Blood culture bottle ; Bronchoalveolar lavage ; Pneumonia
- Abstract
- Background: Pneumonia is a primary cause of morbidity and mortality in infectious disease, and increasing antimicrobial resistance has raised concerns of treatment failure. Therefore, we evaluated the value of a blood culture bottle for bronchoalveolar lavage (BAL) samples on pathogen identification and on treatment modification in patients with pneumonia.
Methods: We conducted a prospective study and enrolled 39 patients who were hospitalized for pneumonia. Enrolled patients underwent BAL; a 10-ml aliquot was transferred to a sterile container for standard quantitative culture, and a 5 ml aliquot was transferred to both an aerobic and an anaerobic blood culture bottle.
Results: Microbes were detected in all 39 (100 %) specimens and possible pathogens were identified in 34 patients (84.6 %) from BAL blood culture bottles. In contrast, microbes were detected in 10 patients (25.6 %) and possible pathogens were isolated in 8 patients (20.5 %) in BAL fluid using conventional culture methods. Finally, 8 of 39 (20.5 %) patients changed antibiotics according to the BAL blood culture results and pneumonia improved in 6 of these patients.
Conclusions: Using blood culture bottles for BAL sampling in patients with pneumonia is a sensitive method to detect pathogens in order to identify an adequate antibiotic treatment regimen.
- ISSN
- 1471-2334
- Language
- English
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