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High prevalence of current asthma and active smoking effect among the elderly
- Authors
- Issue Date
- 2003-03-26
- Publisher
- Blackwell Publishing
- Citation
- Clin Exp Allergy. 2002 Dec;32(12):1706-12.
- Keywords
- Adult ; Age Distribution ; Aged ; Asthma/*epidemiology/*etiology/physiopathology ; Bronchial Provocation Tests ; Bronchoconstrictor Agents/diagnostic use ; Female ; Humans ; Hypersensitivity, Immediate/epidemiology ; Korea/epidemiology ; Logistic Models ; Lung/physiopathology ; Male ; Methacholine Chloride/diagnostic use ; Middle Aged ; Prevalence ; Rural Health ; Skin Tests ; Smoking/*adverse effects/epidemiology ; Urban Health
- Abstract
- BACKGROUND: Although asthma is a common cause of morbidity in adults, relatively few objectively measured population studies of asthma prevalence in adult populations have been conducted. OBJECTIVE: To evaluate the prevalence of asthma, based on both a questionnaire and methacholine bronchial provocation test, and to determine the risk factors of asthma prevalence in an adult population. METHODS: A total of 2,467 adults, who were randomly selected from metropolitan urban, non-metropolitan urban and rural areas, responded to the modified ISAAC questionnaire, and underwent methacholine bronchial provocation tests and skin prick tests to locally common aeroallergens. RESULTS: The prevalence of current asthma based on the questionnaire and the methacholine challenge was 2.0% in adults younger than 40, 3.8% in 40- to 54-year-olds, 7.7% in 55- to 64-year-olds and 12.7% in those aged 65 or higher. For subjects of 55-64 years, active smoking was found to be significantly related with the prevalence of current asthma and bronchial hyper-responsiveness, although smoking was positively associated with percentage predictive value of forced expiratory volume of 1 s (FEV1). CONCLUSION: The prevalence of current asthma is common among the elderly, and active smoking may play an important role in the development of asthma and bronchial hyper-responsiveness among the elderly.
- ISSN
- 0954-7894 (Print)
- Language
- English
- URI
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12653160
https://hdl.handle.net/10371/11789
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