Design and fabrication of unconventional soft materials for implantable medical and optoelectronic devices

Abstract

Soft electronics provide new opportunities on biomedical devices and optoelectronic devices since they offer flexible and conformable mechanical properties. Compared to commercialized rigid electronics, the soft electronics enables more accurate sensing from the curvilinear biological interface and tunable light incidence for optoelectronics. In this thesis, fabrication and application of soft medical devices and unconventional optoelectronic devices are developed based on the design and synthesis of bioresorbable and perovskite materials. Firstly, soft bioresorbable medical devices are designed and fabricated, which provide novel therapeutic guideline to overcome many challenges remaining for the treatment of glioblastoma. The integrated bioresorbable devices are composed of wireless heater, wireless temperature sensor and synthesized bioresorbable drug reservoir conformally adhered to the brain tissue provides localized, highly penetrative and controllable intracranial drug delivery. Based on the fabrication technique of bioresorbable materials, transient memory system is proposed and developed, which shows fast and complete chemical destruction of stored data by wide-range optical stimulation. The system can be established by the integration of transient ultrathin resistive random access memory (RRAM) with multi-dye-sensitized upconverting nanoparticles (UCNPs) and provides new opportunities in mobile and defense application. The final goal of this study is high-definition patterning of inorganic-organic hybrid perovskite thin films which have attracted great attention since it is regarded as an alternative to silicon in the optoelectronic devices. A new method so called Spin-on-patterning (SoP) enables the patterning of perovskite thin film which has hardly been accomplished due to their extreme instability in solvents like bioresorbable materials. The patterned perovskite photodiode is fabricated and has potential for future ultrathin image sensor array.