Publications
Detailed Information
Reliability of Diffusion-Tensor Imaging Measurement Parameters in Cervical Spondylotic Myelopathy : 압박성 경추 척수증의 확산 텐서 영상: 변수 측정 방법의 신뢰도 평가
DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | 이준우 | - |
dc.contributor.author | 이영준 | - |
dc.date.accessioned | 2017-07-14T01:18:21Z | - |
dc.date.available | 2017-07-14T01:18:21Z | - |
dc.date.issued | 2016-02 | - |
dc.identifier.other | 000000132280 | - |
dc.identifier.uri | https://hdl.handle.net/10371/121822 | - |
dc.description | 학위논문 (박사)-- 서울대학교 대학원 : 의과대학 임상의과학과, 2016. 2. 이준우. | - |
dc.description.abstract | Introduction: The goal of this study was to assess inter and intra-observer reliability in cervical spinal cord diffusion-tensor imaging (DTI) in cases of cervical spondylotic myelopathy (CSM), as well as agreement among three different ROI measurement methods.
Methods: Institutional Review Board approval and informed consent were obtained for this study. From July of 2013 until December of 2013, 34 patients (12 male, 22 female | - |
dc.description.abstract | mean age 58.7 years, range 45-79 years) who underwent surgical decompression due to CSM with pre-operative DTIs were retrospectively enrolled. Four observers independently measured the fractional anisotropy (FA) values twice, using 3 different measurement methods, and a spine segment was selected for each disc level, from C1/2 to C7/T1. Inter and intra-observer reliability were assessed by interclass correlation coefficients (ICCs) and, for the test-retest reliability, the Cronbachs alpha was calculated for each observer. The differences in the mean FA values from C1/2 through C7/T1 of all of the study subjects were assessed using a paired sample T-test.
Results: The overall agreement among the 4 observers varied according to the spinal cord level and measurement methods used, ranging from poor to excellent agreement (ICC = 0.374-0.821), with relatively lower agreements in the sagittal ROI method. The radiology resident and neuro-radiologist (observers 3 and 4) showed excellent intra-observer agreement in almost every spinal cord level (ICC = 0.887-0.997). However, the inter-observer agreements varied, with fair to good agreement (ICC = 0.404-0.747). Furthermore, there was a statistically significant difference in the mean FA values from C1/2 through C7/T1 in all three measurement methods. Conclusions: As a diagnostic tool, measured data from the DTI should have high reliability and reproducibility. In spite of the excellent intra-observer reliability of the ROI measurements, the FA values in the patients with CSM had a wide range of variation in inter-observer reliability in our study. Therefore, we should pay more attention to the interpretation of the DTI parameter for clinical usage. | - |
dc.description.tableofcontents | Introduction 1
Material and Methods 4 Study Subjects 4 DTI Protocol 5 Image and Measurement Analysis 7 Statistical Analysis 12 RESULTS 14 DISCUSSION 31 References 39 Abstract in Korean 45 | - |
dc.format | application/pdf | - |
dc.format.extent | 598906 bytes | - |
dc.format.medium | application/pdf | - |
dc.language.iso | en | - |
dc.publisher | 서울대학교 대학원 | - |
dc.subject | Cervial spondylotic Myelopathy | - |
dc.subject | Diffusion Tensor Imaging | - |
dc.subject | Fractional Anisotropy | - |
dc.subject | Magnetic Resonance Imaging | - |
dc.subject | Reliability | - |
dc.subject.ddc | 610 | - |
dc.title | Reliability of Diffusion-Tensor Imaging Measurement Parameters in Cervical Spondylotic Myelopathy | - |
dc.title.alternative | 압박성 경추 척수증의 확산 텐서 영상: 변수 측정 방법의 신뢰도 평가 | - |
dc.type | Thesis | - |
dc.contributor.AlternativeAuthor | Eugene Lee | - |
dc.description.degree | Doctor | - |
dc.citation.pages | vii, 46 | - |
dc.contributor.affiliation | 의과대학 임상의과학과 | - |
dc.date.awarded | 2016-02 | - |
- Appears in Collections:
- Files in This Item:
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.