Fabrication of Peptide Nanofilms by Langmuir-Blodgett and Langmuir-Schaefer Method

Abstract

Tyrosine-containing peptide which can form self-assembled nanostructures has received much attention for various applications such as bio-catalyst, organic conducting film, and ion-selective membrane. In previous study, which 2D nanofilm formation of YYACAYY was reported on a surface of water droplet was driven by pi-pi interactions and stabilization by cross-linked cysteine. In this thesis, new fabrication methods to form large-scale and thickness-controllable nanofilms of YYACAYY were developed, which are called Langmuir-Blodgett (LB) and Langmuir-Schaefer (LS). YYACAYY showed typical surfactant properties, which was proved by the isotherm test (surface pressure - area) by spreading the YYACAYY solution in DMSO on air/water interface. Uniform and flat peptide nanofilms were successfully fabricated, characterized, and evaluated for possible electronic applications.