Publications
Detailed Information
Improving results of the Fontan procedure in patients with heterotaxy syndrome
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Soo-Jin | - |
dc.contributor.author | Kim, Woong-Han | - |
dc.contributor.author | Lim, Hong Gook | - |
dc.contributor.author | Lee, Chang-Ha | - |
dc.contributor.author | Lee, Jae Young | - |
dc.date.accessioned | 2009-11-18T05:38:12Z | - |
dc.date.available | 2009-11-18T05:38:12Z | - |
dc.date.issued | 2006-09-26 | - |
dc.identifier.citation | Ann Thorac Surg. 2006 Oct;82(4):1245-51. | en |
dc.identifier.issn | 1552-6259 (Electronic) | - |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16996916 | - |
dc.identifier.uri | https://hdl.handle.net/10371/13086 | - |
dc.description.abstract | BACKGROUND: The Fontan operation in patients with heterotaxy syndrome has been associated with a poor prognosis. We studied whether the outcome of those patients with heterotaxy syndrome improved compared with those who did not have the syndrome after an extracardiac Fontan operation. METHODS: A retrospective review was performed on 185 patients who had undergone an extracardiac Fontan operation between 1996 and 2005. RESULTS: Sixty-two of the patients had heterotaxy syndrome (33.5%). Forty-one had right isomerism and 21 had left isomerism. Heterotaxy syndrome was commonly associated with a morphologic right ventricle (59.7%), a common atrioventricular valve (72.6%), an interrupted inferior vena cava (25.8%), a separate hepatic vein (30.6%), and extracardiac pulmonary venous drainage (16.1%). The hospital mortality rate was higher in the heterotaxy syndrome than nonheterotaxy (4.8% vs 2.4%; p = 0.05). Eight-year survivals were 91.9 +/- 3.2% in the nonheterotaxy group and 89.3 +/- 4.2 % in the heterotaxy group (p = 0.39). At 8 years, freedom from reoperation was 90.2 +/- 3.2% in the nonheterotaxy group and 78.5 +/- 6.2% in the heterotaxy group (p = 0.15). The outcomes (other than those of arrhythmia) were no different between the two groups. The incidences of early and late postoperative arrhythmia were 29.0% and 25.4%, respectively, in heterotaxy patients, and 15.4% and 10.8% in nonheterotaxy patients (p < 0.05). Bradyarrhythmia was found to be more common. During follow-up, atrioventricular valve regurgitation of more than mild was more common in heterotaxy patients (33.9% vs 18.9%; p = 0.05). CONCLUSIONS: Midterm outcomes after an extracardiac Fontan operation in heterotaxy and nonheterotaxy patients are similar, except arrhythmia and atrioventricular valve regurgitation. | en |
dc.language.iso | en | en |
dc.publisher | Elsevier | en |
dc.subject | Arrhythmias, Cardiac/etiology | en |
dc.subject | Child | en |
dc.subject | Child, Preschool | en |
dc.subject | Female | en |
dc.subject | Heart Defects, Congenital/mortality/*surgery | en |
dc.subject | Humans | en |
dc.subject | Infant | en |
dc.subject | Male | en |
dc.subject | Prognosis | en |
dc.subject | Reoperation | en |
dc.subject | Retrospective Studies | en |
dc.subject | Survival Analysis | en |
dc.subject | Syndrome | en |
dc.subject | Treatment Outcome | en |
dc.subject | Fontan Procedure/adverse effects | - |
dc.title | Improving results of the Fontan procedure in patients with heterotaxy syndrome | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 김수진 | - |
dc.contributor.AlternativeAuthor | 김웅한 | - |
dc.contributor.AlternativeAuthor | 임홍국 | - |
dc.contributor.AlternativeAuthor | 이창하 | - |
dc.contributor.AlternativeAuthor | 이재영 | - |
dc.identifier.doi | 10.1016/j.athoracsur.2006.04.082 | - |
- Appears in Collections:
- Files in This Item:
- There are no files associated with this item.
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.