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Low-Tube-Voltage, Half-Dose Multidetector Liver CT with Sinogram-Affirmed Iterative Reconstruction (SAFIRE) Algorithm for Detection of Hypervascular Hepatocellular Carcinoma : 고혈관성 간세포암 발견을 위한 Sinogram-Affirmed Iterative Reconstruction (SAFIRE) 알고리즘을 이용한 저전압, 절반선량 다배열검출기 간 전산화단층촬영
DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | 이정민 | - |
dc.contributor.author | 유미혜 | - |
dc.date.accessioned | 2017-07-19T10:09:32Z | - |
dc.date.available | 2017-07-19T10:09:32Z | - |
dc.date.issued | 2013-02 | - |
dc.identifier.other | 000000008428 | - |
dc.identifier.uri | https://hdl.handle.net/10371/132346 | - |
dc.description | 학위논문 (석사)-- 서울대학교 대학원 : 임상의과학과, 2013. 2. 이정민. | - |
dc.description.abstract | Introduction: The purpose of this study was to compare the image quality and lesion detectability of low-tube-voltage, half-dose liver CT reconstructed using sinogram–affirmed iterative reconstruction (SAFIRE) algorithm with full-dose scans using filtered back projection (FBP) algorithm for hypervascular hepatocellular carcinoma (HCC).
Methods: A total of 126 patients with suspected HCCs and who underwent liver CT including arterial phase scanning at 80-kVp in the dual-source mode (300-mAs for each tube), were included in this study. The half-dose arterial scans were reconstructed using FBP, iterative reconstruction in image space (IRIS), and five different SAFIRE strengths (S1-S5), respectively, and were compared with full-dose virtual scans (600-mA) reconstructed using FBP. I assessed the image noise, contrast-to-noise ratio (CNR) of the liver, vessels, and CNRlesion-to-liver . Two radiologists evaluated the image quality and lesion detectability on the different image sets. Results: The image noise on SAFIRE images was significantly lower and the CNRs on SAFIRE images were higher than those on half-dose FBP images (p < 0.001). In addition, CNRlesion-to-liver on half-dose SAFIRE images with S5 was higher than on IRIS and full-dose FBP images (p < 0.05). Among the half-dose scans, SAFIRE images showed significantly better image quality than FBP images (p < 0.05). Regarding lesion detection, half-dose SAFIRE images were better than half-dose FBP images and were comparable with full-dose FBP images (91.8% vs. 96%, observer 1 and 98% vs. 98%, observer 2, p > 0.05). Conclusions: Half-dose, 80-kVp liver CT using SAFIRE technique may increase the image quality and provide comparable lesion detectability of hypervascular HCC at a reduced radiation dose compared with full-dose CT with FBP. | - |
dc.description.tableofcontents | 영문초록...........................................i
목차 ...........................................iii List of Table.....................................iv List of Figures....................................v Introduction.......................................1 Materials and Methods..............................3 Results...........................................13 Discussion........................................28 References........................................34 국문초록..........................................40 | - |
dc.format | application/pdf | - |
dc.format.extent | 1431867 bytes | - |
dc.format.medium | application/pdf | - |
dc.language.iso | en | - |
dc.publisher | 서울대학교 대학원 | - |
dc.subject | Iterative reconstruction | - |
dc.subject | low tube voltage | - |
dc.subject | dose reduction | - |
dc.subject | noise reduction | - |
dc.subject | liver CT | - |
dc.subject | sinogram-affirmed iterative reconstruction (SAFIRE) | - |
dc.title | Low-Tube-Voltage, Half-Dose Multidetector Liver CT with Sinogram-Affirmed Iterative Reconstruction (SAFIRE) Algorithm for Detection of Hypervascular Hepatocellular Carcinoma | - |
dc.title.alternative | 고혈관성 간세포암 발견을 위한 Sinogram-Affirmed Iterative Reconstruction (SAFIRE) 알고리즘을 이용한 저전압, 절반선량 다배열검출기 간 전산화단층촬영 | - |
dc.type | Thesis | - |
dc.contributor.AlternativeAuthor | Mi Hye Yu | - |
dc.description.degree | Master | - |
dc.citation.pages | 41 | - |
dc.contributor.affiliation | 의과대학 임상의과학과 | - |
dc.date.awarded | 2013-02 | - |
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