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Outcomes of Repair of Coarctation of Aorta with Hypoplastic Arch Using Extended End-to-Side Anastomosis Technique : 대동맥궁 형성저하가 동반된 대동맥 교악증 환아에서 확장 단측문합술의 효용성과 치료성적에 대한 연구

DC Field Value Language
dc.contributor.advisor김웅한-
dc.contributor.author김응래-
dc.date.accessioned2017-07-19T10:16:13Z-
dc.date.available2017-07-19T10:16:13Z-
dc.date.issued2017-02-
dc.identifier.other000000142744-
dc.identifier.urihttps://hdl.handle.net/10371/132497-
dc.description학위논문 (석사)-- 서울대학교 대학원 : 임상의과학과, 2017. 2. 김웅한.-
dc.description.abstractIntroduction: The optimal surgical repair technique for coarctation associated with aortic arch hypoplasia (CoA/AAH) in neonates and infants is controversial. This study evaluates our current strategy utilizing extended end-to-side anastomosis (EESA) under selective cerebral and myocardial perfusion (SCMP) in treating this group of patients.
Methods: Through a retrospective review, we analyzed the outcome of 87 infants who underwent surgical repair of CoA/AAH from January 2004 to December 2015.Patients with functional single ventricle were excluded.
Results: There were no early mortalities and 4 patients (4.6%) experienced early complications. Eighty-five patients (97.7%) were followed-up during a mean duration of 6.1± 3.53 years. There were 2 late mortalities (2.3%) and 3 re-intervention (3.5%) of the aortic arch. Ten-year overall survival and freedom from re-intervention for the entire cohort was 97.7% and 96.3%, respectively. At last follow-up, 4 patients (4.5%) showed a peak velocity greater than 2.5m/s across the repair site.7patients (8.2%) were hypertensive. Among 44 patients (50.6%) with post-operative CT data, 7 patients (15.9%) showed gothic shaped arches. In the present study, we could not correlate arch geometry with increased blood pressure.
Conclusions: Our strategy with EESA under SCMP is safe and effective for repairing CoA/AAH in neonates and infants. Concomitant repair of associated cardiac anomalies can be done without added risk. Surgical results are excellent with low rates of mortality, re-intervention, and late hypertension.
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dc.description.tableofcontents1.Introduction 1
2.Materials and Methods 5
2.1.Study subjects 5
2.2.Surgical technique 5
2.3.Data collection and follow-up methods 7
2.4.Blood pressure and arch geometry analysis 8
2.5.Statistical Analysis 10
3.Results 12
3.1.Patient demographics 12
3.2.Early post-operative results 14
3.3.Late post-operative results 14
3.4.Aortic Arch Geometry 20
4.Discussion 23
5.Conclusion 29
References 30
초록 36
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dc.formatapplication/pdf-
dc.format.extent698595 bytes-
dc.format.mediumapplication/pdf-
dc.language.isoen-
dc.publisher서울대학교 대학원-
dc.subjectCoarctation of Aorta-
dc.subjectHypoplastic Arch-
dc.subjectExtended end-to-side anastomosis-
dc.subject.ddc610-
dc.titleOutcomes of Repair of Coarctation of Aorta with Hypoplastic Arch Using Extended End-to-Side Anastomosis Technique-
dc.title.alternative대동맥궁 형성저하가 동반된 대동맥 교악증 환아에서 확장 단측문합술의 효용성과 치료성적에 대한 연구-
dc.typeThesis-
dc.description.degreeMaster-
dc.citation.pages37-
dc.contributor.affiliation의과대학 임상의과학과-
dc.date.awarded2017-02-
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