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Outcomes of Repair of Coarctation of Aorta with Hypoplastic Arch Using Extended End-to-Side Anastomosis Technique : 대동맥궁 형성저하가 동반된 대동맥 교악증 환아에서 확장 단측문합술의 효용성과 치료성적에 대한 연구
DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | 김웅한 | - |
dc.contributor.author | 김응래 | - |
dc.date.accessioned | 2017-07-19T10:16:13Z | - |
dc.date.available | 2017-07-19T10:16:13Z | - |
dc.date.issued | 2017-02 | - |
dc.identifier.other | 000000142744 | - |
dc.identifier.uri | https://hdl.handle.net/10371/132497 | - |
dc.description | 학위논문 (석사)-- 서울대학교 대학원 : 임상의과학과, 2017. 2. 김웅한. | - |
dc.description.abstract | Introduction: The optimal surgical repair technique for coarctation associated with aortic arch hypoplasia (CoA/AAH) in neonates and infants is controversial. This study evaluates our current strategy utilizing extended end-to-side anastomosis (EESA) under selective cerebral and myocardial perfusion (SCMP) in treating this group of patients.
Methods: Through a retrospective review, we analyzed the outcome of 87 infants who underwent surgical repair of CoA/AAH from January 2004 to December 2015.Patients with functional single ventricle were excluded. Results: There were no early mortalities and 4 patients (4.6%) experienced early complications. Eighty-five patients (97.7%) were followed-up during a mean duration of 6.1± 3.53 years. There were 2 late mortalities (2.3%) and 3 re-intervention (3.5%) of the aortic arch. Ten-year overall survival and freedom from re-intervention for the entire cohort was 97.7% and 96.3%, respectively. At last follow-up, 4 patients (4.5%) showed a peak velocity greater than 2.5m/s across the repair site.7patients (8.2%) were hypertensive. Among 44 patients (50.6%) with post-operative CT data, 7 patients (15.9%) showed gothic shaped arches. In the present study, we could not correlate arch geometry with increased blood pressure. Conclusions: Our strategy with EESA under SCMP is safe and effective for repairing CoA/AAH in neonates and infants. Concomitant repair of associated cardiac anomalies can be done without added risk. Surgical results are excellent with low rates of mortality, re-intervention, and late hypertension. | - |
dc.description.tableofcontents | 1.Introduction 1
2.Materials and Methods 5 2.1.Study subjects 5 2.2.Surgical technique 5 2.3.Data collection and follow-up methods 7 2.4.Blood pressure and arch geometry analysis 8 2.5.Statistical Analysis 10 3.Results 12 3.1.Patient demographics 12 3.2.Early post-operative results 14 3.3.Late post-operative results 14 3.4.Aortic Arch Geometry 20 4.Discussion 23 5.Conclusion 29 References 30 초록 36 | - |
dc.format | application/pdf | - |
dc.format.extent | 698595 bytes | - |
dc.format.medium | application/pdf | - |
dc.language.iso | en | - |
dc.publisher | 서울대학교 대학원 | - |
dc.subject | Coarctation of Aorta | - |
dc.subject | Hypoplastic Arch | - |
dc.subject | Extended end-to-side anastomosis | - |
dc.subject.ddc | 610 | - |
dc.title | Outcomes of Repair of Coarctation of Aorta with Hypoplastic Arch Using Extended End-to-Side Anastomosis Technique | - |
dc.title.alternative | 대동맥궁 형성저하가 동반된 대동맥 교악증 환아에서 확장 단측문합술의 효용성과 치료성적에 대한 연구 | - |
dc.type | Thesis | - |
dc.description.degree | Master | - |
dc.citation.pages | 37 | - |
dc.contributor.affiliation | 의과대학 임상의과학과 | - |
dc.date.awarded | 2017-02 | - |
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