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Inter-eye differences in myopic patients with unilateral normal-tension glaucoma : 단안 정상안압녹내장을 가진 근시 환자에서 양안간의 차이
DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | 김동명 | - |
dc.contributor.author | 오원혁 | - |
dc.date.accessioned | 2017-07-19T10:21:57Z | - |
dc.date.available | 2017-07-19T10:21:57Z | - |
dc.date.issued | 2014-02 | - |
dc.identifier.other | 000000016662 | - |
dc.identifier.uri | https://hdl.handle.net/10371/132613 | - |
dc.description | 학위논문 (석사)-- 서울대학교 대학원 : 의학과(안과학전공), 2014. 2. 김동명. | - |
dc.description.abstract | Purpose: To compare the extent of myopia and axial length (AL) along with other ocular risk factors for the development of open-angle glaucoma between two eyes in bilaterally myopic patients with unilateral normal-tension glaucoma (NTG).
Methods: Bilaterally myopic patients with unilateral NTG were consecutively enrolled for this study. Comparison between 2 eyes was performed with regard to intraocular pressure (IOP), mean deviation (MD) and pattern standard deviation (PSD) of the visual field (VF), spectral-domain optical coherence tomography parameters (circumpapillary retinal nerve fiber layer [cpRNFL] thickness, disc area, β-zone parapapillary atrophy [PPA] area), refractive error, and AL. Results: Thirty-six bilaterally myopic patients with unilateral NTG (21 men and 15 women, 41.6 ± 9.3 years) were included. Untreated mean and highest IOP in NTG eyes were not significantly different from those in contralateral non-glaucomatous eyes. VF parameters were worse in NTG eyes than in contralateral non-glaucomatous eyes. The average, superior and inferior quadrants of cpRNFL thickness in NTG eyes were thinner than those in contralateral non-glaucomatous eyes. Compared with contralateral non-glaucomatous eyes, the disc area in NTG eyes was smaller (1.91 ± 0.54 mm2 vs. 2.02 ± 0.50 mm2, p = 0.040), but the β-zone PPA area in NTG eyes was larger (1.40 ± 0.75 mm2 vs. 0.98 ± 0.56 mm2, p < 0.001). NTG eyes had more myopic refractive error and longer AL than contralateral non-glaucomatous eyes (-5.73 ± 1.87 D vs. -4.92 ± 2.01 D, p < 0.001 | - |
dc.description.abstract | 26.42 ± 1.04 mm vs. 26.08 ± 1.11 mm, p < 0.001).
Conclusions: In bilaterally myopic individuals, NTG eyes had more myopic refractive error, longer AL, and larger β-zone PPA areas than contralateral non-glaucomatous eyes. These inter-eye differences in the levels of risk factors for open-angle glaucoma may have contributed to the development of unilateral NTG in myopes. | - |
dc.description.tableofcontents | Abstract……………………………………………………………ⅰ
Contents……………………………………………………………ⅲ List of Tables……………………………………………………ⅳ List of Figures……………………………………………………ⅴ Introduction…………………………………………………………1 Materials and Methods……………………………………………3 Results………………………………………………………………7 Discussion…………………………………………………………19 Conclusions…………………………………………………………23 References…………………………………………………………24 국문초록…………………………………………………………29 | - |
dc.format | application/pdf | - |
dc.format.extent | 642950 bytes | - |
dc.format.medium | application/pdf | - |
dc.language.iso | en | - |
dc.publisher | 서울대학교 대학원 | - |
dc.subject | 정상안압녹내장 | - |
dc.subject | 근시 | - |
dc.subject | 안축장 | - |
dc.subject | β 영역 시신경유두주위 위축 | - |
dc.subject.ddc | 610 | - |
dc.title | Inter-eye differences in myopic patients with unilateral normal-tension glaucoma | - |
dc.title.alternative | 단안 정상안압녹내장을 가진 근시 환자에서 양안간의 차이 | - |
dc.type | Thesis | - |
dc.description.degree | Master | - |
dc.citation.pages | ⅴ, 30 | - |
dc.contributor.affiliation | 의과대학 의학과 | - |
dc.date.awarded | 2014-02 | - |
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