S-Space College of Medicine/School of Medicine (의과대학/대학원) Dept. of Medicine (의학과) Theses (Master's Degree_의학과)
Ultrasonically activated shears can reduce estimated blood loss in open distal gastrectomy for gastric cancer: A randomized controlled study
위암 환자의 개복 위아전절제술에서의 초음파절삭기 사용으로 인한 실혈량 감소: 전향적 무작위 임상시험
- 의과대학 의학과
- Issue Date
- 서울대학교 대학원
- 학위논문 (석사)-- 서울대학교 대학원 : 의학과, 2014. 2. 양한광.
- Introduction: Although UAS have been used increasingly in open gastric surgery, only a limited number of randomized controlled studies have evaluated its safety and efficacy for this procedure. In addition, these studies used only a small number of patients or did not control for the type of anastomosis or surgery.
Methods: From October 2011 to November 2012, 56 gastric cancer patients eligible for open distal gastrectomy were randomized into a UAS dissection group (USD group) or a monopolar dissection group (MPD group
clinical trial registration number: NCT01971775). The primary endpoints were the estimated blood loss during surgery and amount of drainage through the 5th postoperative day. Secondary endpoints were operation time, hospital stay, serum laboratory results, inflammatory cytokine levels in the serum and peritoneal irrigation saline, cytology, and postoperative morbidity.
Results: The demographics and pathologic parameters were similar in both groups. The estimated blood loss was lower in the USD group than that in the MPD group (339.8 cc vs. 428.6 cc, p = 0.021). However, the amount of postoperative drainage was not significantly different between the two groups. In terms of the secondary endpoints, no statistical differences were observed between the two groups.
Conclusions: UAS can reduce blood loss and can be an alternative device for conventional monopolar electrocautery in open distal gastrectomy for gastric cancer.