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Efficacy of a Topical Gelatin-Thrombin Matrix Sealant in Reducing Postoperative Drainage Following Anterior Cervical Discectomy and Fusion : 전방 경추 추간판 제거술 및 유합술 후 적용되는 국소 Gelatin-Thrombin Matrix Sealant가 수술 후 배액량 감소에 미치는 효용성
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- Authors
- Advisor
- 염진섭
- Major
- 의과대학 의학과
- Issue Date
- 2016-02
- Publisher
- 서울대학교 대학원
- Keywords
- Cervical vertebrae ; Hemostasis ; Postoperative hemorrhage ; Floseal matrix ; Spinal fusion
- Description
- 학위논문 (석사)-- 서울대학교 대학원 : 의학과 정형외과학 전공, 2016. 2. 염진섭.
- Abstract
- Study Design: Retrospective fusion level(s)-, age-, and gender-matched analysis.
Purpose: To determine whether the application of a topical gelatin-thrombin matrix sealant (Floseal) at the end of anterior cervical discectomy and fusion (ACDF) can reduce the amount of postoperative hemorrhage.
Overview of Literature: The effect of the matrix sealant in decreasing postoperative hemorrhage following ACDF has not been reported.
Methods: Matrix sealant was (n=116, study group) or was not applied (n=58, control group) at the end of ACDF. Patients were se¬lected by 1:2 matching criteria of fusion level(s), age, and gender. Seven parameters described below were compared between the two groups.
Results: The total drain amount for the first 24 hours (8±9 versus 27±22 mL), total drain amount until the 8-hour drainage decreased to ≤10 mL (8±10 versus 33±26 mL), and the total drain amount until 6 AM on the first postoperative day (7±8 versus 24±20 mL) were significantly lower in the study group than the control group (all p <0.001).
Conclusions: Application of the topical matrix sealant at the end of ACDF can significantly reduce the amount of postoperative hemorrhage.
- Language
- English
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