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Association between Urinary 3-Phenoxybenzoic Acid and Body Mass Index in Korean adults : 1st Korean National Environmental Health Survey : 요중 3-페녹시벤조익산과 체질량 지수의 관련성
DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | 홍윤철 | - |
dc.contributor.author | 유민상 | - |
dc.date.accessioned | 2017-07-19T10:33:54Z | - |
dc.date.available | 2017-07-19T10:33:54Z | - |
dc.date.issued | 2016-02 | - |
dc.identifier.other | 000000133749 | - |
dc.identifier.uri | https://hdl.handle.net/10371/132865 | - |
dc.description | 학위논문 (석사)-- 서울대학교 대학원 : 의학과 예방의학 전공, 2016. 2. 홍윤철. | - |
dc.description.abstract | Objective: We investigated the association between pyrethroid exposure and obesity in a national representative cross-sectional study. In addition, we evaluated the differences in the association between pyrethroid exposure and obesity depending on the exposure levels.
Method:We used data of 3,671 participants aged above 19 from the Korean National 1 Environmental Health Survey in 2009-2011. In our analysis, multivariate piece-wise regression and logistic regression analysis were used to investigate the association between urinary 3-PBA (3-Phenoxybenzoic Acid) and BMI. Result: Log-transformed level of urinary 3-PBA had significantly positive association with BMI at the low-level range of exposure (p<0.0001), and opposite associations were observed at the high level exposure (p=0.04) after adjusting covariates. In piece-wise regression analysis, the flexion point that changes direction of the associations was at around 4 ug/g creatinine of urinary 3-PBA. As quintiles based on concentration of urinary 3-PBA increased to Q4, the ORs for prevalence of overweight (BMI ≥ 23kg/m2) were increased, and the OR of Q5 was lower than that of Q4 (OR = 1.810 for Q4 | - |
dc.description.abstract | OR = 1.483 for Q5). In the analysis using obesity (BMI ≥ 25kg/m2) as outcome variable, significant associations were observed between obesity and quintiles of 3-PBA, however, there were no differences between the OR of Q5 and that of Q4 (OR = 1.659 for Q4 | - |
dc.description.abstract | OR = 1.666 for Q5).
Conclusion: Our analysis suggested that low-level of pyrethroid exposure has positive association with BMI, however, there is an inverse relationship above the urinary 3-PBA level at 4 ug/g creatinine. | - |
dc.description.tableofcontents | Introduction 4
Materials and method 6 Ethics Statement 6 Study participants 6 Variables 6 Statistical analysis 7 Results 10 Discussion 14 Reference 21 국문초록 37 | - |
dc.format | application/pdf | - |
dc.format.extent | 3618248 bytes | - |
dc.format.medium | application/pdf | - |
dc.language.iso | en | - |
dc.publisher | 서울대학교 대학원 | - |
dc.subject | pyrethroid | - |
dc.subject | 3-phenoxybenzoic acid | - |
dc.subject | overweight | - |
dc.subject | obesity | - |
dc.subject | BMI | - |
dc.subject | KNEHS | - |
dc.subject.ddc | 610 | - |
dc.title | Association between Urinary 3-Phenoxybenzoic Acid and Body Mass Index in Korean adults : 1st Korean National Environmental Health Survey | - |
dc.title.alternative | 요중 3-페녹시벤조익산과 체질량 지수의 관련성 | - |
dc.type | Thesis | - |
dc.contributor.AlternativeAuthor | Minsang Yoo | - |
dc.description.degree | Master | - |
dc.citation.pages | 38 | - |
dc.contributor.affiliation | 의과대학 의학과 | - |
dc.date.awarded | 2016-02 | - |
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