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Gamma knife radiosurgery for central neurocytoma: primary and secondary treatment

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dc.contributor.authorKim, Chae-Yong-
dc.contributor.authorPaek, Sun Ha-
dc.contributor.authorJeong, Sang Soon-
dc.contributor.authorChung, Hyun-Tai-
dc.contributor.authorHan, Jung Ho-
dc.contributor.authorPark, Chul-Kee-
dc.contributor.authorJung, Hee-Won-
dc.contributor.authorKim, Dong Gyu-
dc.date.accessioned2009-11-19T03:49:48Z-
dc.date.available2009-11-19T03:49:48Z-
dc.date.issued2007-10-11-
dc.identifier.citationCancer. 2007 Nov 15;110(10):2276-84.en
dc.identifier.issn0008-543X (Print)-
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17926332-
dc.identifier.urihttps://hdl.handle.net/10371/13614-
dc.description.abstractBACKGROUND: Little is known about long-term results of gamma knife (GK) stereotactic radiosurgery (SRS) as a primary or a secondary postoperative therapy for central neurocytomas (CNs). The authors retrospectively reviewed long-term outcomes of 13 patients with CN treated with GK SRS. METHODS: Thirteen patients were treated with GK SRS as a primary (6 patients) or a secondary postoperative therapy (7 patients). Follow-up clinical status and brain magnetic resonance imaging (MRI) were thoroughly analyzed. The functional status of patients was assessed with the Karnofsky Performance Scale during follow-up. RESULTS: The median follow-up period for clinical status and imaging studies was 61 months (range, 6 months to 96 months). Tumors decreased in 5 patients who received GK SRS as a primary treatment. However, the tumor recurred in 2 patients treated with a secondary GK SRS after surgery from the residual tumor bed that was not covered by the GK SRS. Parenchymal changes and secondary malignancies were not found in follow-up MRIs of all 13 patients. The Karnofsky Performance Scale score of all patients, except for 1 patient who suffered from an unrelated anteriorly communicating arterial aneurysmal rupture, did not change after GK SRS. CONCLUSIONS: GK SRS may be useful as a primary or a secondary postoperative therapy for the treatment of CN. However, more attention should be paid to residual or recurrent CN during treatment, and regular long-term follow-up MRI should be mandatory to validate the procedure.en
dc.language.isoenen
dc.publisherJohn Wiley & Sonsen
dc.subjectAdolescenten
dc.subjectAdulten
dc.subjectBrain Neoplasms/*surgeryen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectNeurocytoma/*surgeryen
dc.subjectRetrospective Studiesen
dc.subjectTreatment Outcomeen
dc.subjectRadiosurgery-
dc.titleGamma knife radiosurgery for central neurocytoma: primary and secondary treatmenten
dc.typeArticleen
dc.contributor.AlternativeAuthor김재용-
dc.contributor.AlternativeAuthor백선하-
dc.contributor.AlternativeAuthor정상훈-
dc.contributor.AlternativeAuthor정현태-
dc.contributor.AlternativeAuthor한정호-
dc.contributor.AlternativeAuthor박철기-
dc.contributor.AlternativeAuthor정희원-
dc.contributor.AlternativeAuthor김동규-
dc.identifier.doi10.1002/cncr.23036-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Neurosurgery (신경외과학전공)Journal Papers (저널논문_신경외과학전공)
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