Publications
Detailed Information
Tyrosine Peptide Template-based Palladium Nanoparticle Catalyst for C-C Coupling Reaction and Dityrosine Crosslinked Perylene Diimide for Photocurrent Generation
DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | 이윤식 | - |
dc.contributor.author | 김영오 | - |
dc.date.accessioned | 2017-10-27T16:48:14Z | - |
dc.date.available | 2017-10-27T16:48:14Z | - |
dc.date.issued | 2017-08 | - |
dc.identifier.other | 000000146079 | - |
dc.identifier.uri | https://hdl.handle.net/10371/136876 | - |
dc.description | 학위논문 (박사)-- 서울대학교 대학원 공과대학 화학생물공학부, 2017. 8. 이윤식. | - |
dc.description.abstract | Proteins and peptides systematically assemble into functional systems by using multiple covalent and non-covalent interactions of 20 amino acids. Among various amino acids, tyrosine has unique properties in helping protein folding and facilitating proton-coupled electron transfer. Recently, many efforts have been conducted to apply the tyrosines properties in fabrication of functional material.
In chapter 1, a fabrication method of palladium (Pd) nanostructure using a specifically designed peptide, Tyr-Tyr-Ala-His-Ala-Tyr-Tyr (YYAHAYY), as a template is described. The YYAHAYY peptide induced the formation of flower-like palladium (Pd) nanostructure by controlling its size and shape. The flower-shaped Pd NPs were well-dispersed in water due to the amphiphilic property of YYAHAYY peptide. In addition, the flower-shaped Pd NPs showed excellent catalytic activities in copper-free Sonogashira cross-coupling reaction in water. In chapter 2, a method to self-organize perylene diimides (PDI) into two-dimensional (2D) film at air/water interface through dityrosine crosslinkage is presented. Dityrosine-crosslinking was formed by one-step photo-polymerization of tyrosine-appended PDI without the need of a template. Such assembly is driven by the amphiphilicity of the crosslinked molecules that have the carboxylic group from the tyrosines and the polycyclic aromatic hydrocarbons from the PDIs. Depending on UV irradiation time, the thickness of the film can be controlled. In addition, upon crosslinking, the PDI film is stacked through pi-pi interaction between the PDIs, which induces semi-crystalline property. The resulting dityrosine crosslinked PDI film shows a photo-active property. This simple approach can be expanded into direct fabrication of free-standing and photocurrent generating organic thin films. | - |
dc.description.tableofcontents | Introduction 2
1. Peptide Assembly Based Architectures 3 2. Properties of Tyrosine 11 2.1. Tyrosine as a Structure Forming Inducer 11 2.2 Tyrosine as Redox Mediator 15 2.3. Di-tyrosine as a Crosslinker 18 3. Research Objectives 20 Chapter I. A Tyrosine-rich Peptide Induced Palladium Nanostructure for C-C Coupling Reactions 22 1. Introduction 23 1.1. Peptide as a Template for Synthesis of Metal Nanostructures 23 1.2. Peptide-Templated Metal Nanomaterials as Heterogeneous Catalyst for Various Organic Reactions 28 2. Experimental Section 30 2.1. Chemicals and Materials 30 2.2. Peptide Synthesis 31 2.3. Fabrication of Palladium Nanoparticles 32 2.4. Characterization 33 UV/Vis Spectroscopy 33 Circular Dichroism (CD) Spectroscopy 33 Fourier Transform Infrared Spectroscopy (FT-IR) 33 Transmission Electron Microscope (TEM) 34 Inductively Coupled Plasma-atomic Emission Spectroscopy (ICP-AES) 35 X-ray Diffraction (XRD) Analysis 35 2.5. Copper-free Sonogashira Reaction 36 3. Results and Discussion 37 3.1. Design of Peptide Template for Fabrication of Pd Nanostructure 37 3.2. Characterization of Tyrosine-rich Peptide Induced Flower-like Palladium Nanostructure 42 3.3. Catalytic Properties of Palladium Nanoflower in Copper-free Sonogashira Reaction 53 3.4. Recycling of Palladium Nanoflower 59 3.5. Mechanism of Efficient Catalytic Activities of Palladium Nanoflower in Water 63 4. Conclusion 64 Chapter II. Covalent Self-assembly of Tyrosine-appended Perylene Diimides for Photocurrent Generation 65 1. Introduction 66 1.1. Perylene derivatives and their Properties 66 1.2. Packing and Self-assembly of Perylene Diimides 70 1.3. Perylene Diimides as an Efficient Photocurrent Generator 74 2. Experimental Section 76 2.1. Chemicals and Materials 76 2.2. Synthesis of Tyrosine-conjugated Perylene Diimide 77 2.3. Self-assembly of Tyrosine-conjugated Perylene Diimides by Dityrosine Crosslinking 79 2.4. Characterization 80 Nuclear Magnetic Resonance (NMR) Spectroscopy 80 UV/Vis Spectroscopy 80 Fluorescence (FL) Spectroscopy 81 Transmission Electron Microscope 81 X-ray Diffraction Analysis 82 Transient Absorption Spectra 82 Photocurrent Measurement 83 3. Results and Discussion 85 3.1. Preparation of Crosslinked Free-floating Tyrosine-PDI Film 85 3.2. Characterization of Crosslinked PDI Film 87 3.3. Molecular Mechansim for the Formation of Self-floating Crosslinked PDI Film 100 3.4. Evaluation of Crosslinked Y-PDI film as Photocurrent Generator 103 3.5. Effect of Spacer Amino Acid between Tyrosine and PDI to Photocurrent Generation 112 4. Conclusion 116 References 117 Abstract in Korean 151 | - |
dc.format | application/pdf | - |
dc.format.extent | 3831213 bytes | - |
dc.format.medium | application/pdf | - |
dc.language.iso | en | - |
dc.publisher | 서울대학교 대학원 | - |
dc.subject | Peptide assembly | - |
dc.subject | Self-assembly | - |
dc.subject | Bio-inspired approach | - |
dc.subject | Peptide template | - |
dc.subject | Tyrosine | - |
dc.subject | Dityrosine | - |
dc.subject | Palladium | - |
dc.subject | Catalyst | - |
dc.subject | Cross coupling | - |
dc.subject | Copper-free Sonogashira reaction | - |
dc.subject | Organic semiconductor | - |
dc.subject | Perylene diimide | - |
dc.subject | Photocurrent | - |
dc.subject.ddc | 660.6 | - |
dc.title | Tyrosine Peptide Template-based Palladium Nanoparticle Catalyst for C-C Coupling Reaction and Dityrosine Crosslinked Perylene Diimide for Photocurrent Generation | - |
dc.type | Thesis | - |
dc.description.degree | Doctor | - |
dc.contributor.affiliation | 공과대학 화학생물공학부 | - |
dc.date.awarded | 2017-08 | - |
- Appears in Collections:
- Files in This Item:
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.