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Aesthetically effective dental desensitizer using tannin-metal complexes : 심미적이고 효과적인 상아질 지각과민증 처치용 타닌-금속 복합체

DC Field Value Language
dc.contributor.advisor안진수-
dc.contributor.author주성원-
dc.date.accessioned2017-10-27T17:17:17Z-
dc.date.available2017-10-27T17:17:17Z-
dc.date.issued2017-08-
dc.identifier.other000000145764-
dc.identifier.urihttps://hdl.handle.net/10371/137204-
dc.description학위논문 (박사)-- 서울대학교 대학원 치의학대학원 치의과학과, 2017. 8. 안진수.-
dc.description.abstractIntroduction: The aim of this study was to evaluate desensitizing solutions which were made tannin acid ion and various metal ion oxides. Aesthetically improved vis-à-vis significant bioremineralization of the hydroxyapatite (HAp) crystals for the treatment of dentinal hypersensitivity has been explored following the tanin acid-metal (ions and oxides) complex mediated mineralization.
Methods: Demineralized human molar disks were treated with TA combined with 6 different daily intake metal ions and metal oxide namely Sr(NO3)2, SiO2, Fe2O3, TiO2, CaCl2, and VCl3 in separate experiments. The samples were coated in the complex solution for 4 min followed by immersion in artificial saliva for 7 days. Biomineralized HAp crystals were well characterized by Field Emission Scanning Electron microscope (FE-SEM), Transmission Electron Microscope (TEM), Scanning Electron Microscope (SEM) and Selected Area Electron Diffraction (SAED).
Results: TA-Sr(NO3)2 TA-TiO2 exhibited the most significant results by occluding the Ca. 79% and 68% dentinal tubules, respectively with brighter color changes after treatments.
Conclusions: TA combined desensitizing solutions had improved aesthetics of the exposed dentin by its whitening effect using chemically inert and biocompatible, Sr and Ti oxides which may be potential to develop facile at-home aesthetically effective dentin hypersensitivity solution.
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dc.description.tableofcontents1. Introduction

2. Materials and Methods
2.1 Materials
2.2 Preparation of acid-etched tooth slices
2.3 Coating and remineralization methods
2.4 Characterizations of the precipitates of remineralization
2.5 Dentinal fluid permeability assay
2.6 Colorimetric measurement
2.7 Human periodontal ligament (hPDL) cell culture

3. Results and Discussions
3.1 Pyrogallol-mediated HAp remineralization
3.2 Characterizations
3.3 Dentinal fluid test and topological occlusion of dentinal tubules
3.4 Color changes and whiteness index measurements
3.5 Cell proliferation of human periodontal ligament (hPDL) cells

4. Conclusions
References
Figures
Korean Abstract
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dc.formatapplication/pdf-
dc.format.extent925740 bytes-
dc.format.mediumapplication/pdf-
dc.language.isoen-
dc.publisher서울대학교 대학원-
dc.subjectAesthetics-
dc.subjectDentin hypersensitivity-
dc.subjectDentinal tubule-
dc.subjectRemineralization-
dc.subjectTannin-metal complexes-
dc.subject.ddc617.6-
dc.titleAesthetically effective dental desensitizer using tannin-metal complexes-
dc.title.alternative심미적이고 효과적인 상아질 지각과민증 처치용 타닌-금속 복합체-
dc.typeThesis-
dc.contributor.AlternativeAuthorSungwon Ju-
dc.description.degreeDoctor-
dc.contributor.affiliation치의학대학원 치의과학과-
dc.date.awarded2017-08-
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