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Multi-contrast imaging: a Novel Pulse Sequence for Simultaneous Acquisition of Proton Density, T1-Weighted, T2-Weighted and FLAIR Images : 다중 컨트라스트 영상기법: Proton density, T1, T2 및 FLAIR 영상을 동시에 획득하는 펄스시퀀스
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- Authors
- Advisor
- 이종호
- Major
- 공과대학 전기·정보공학부
- Issue Date
- 2017-08
- Publisher
- 서울대학교 대학원
- Keywords
- Magnetic resonance imaging ; multi-contrast ; fast spin-echo ; FLAIR image ; quantitative imaging
- Description
- 학위논문 (석사)-- 서울대학교 대학원 공과대학 전기·정보공학부, 2017. 8. 이종호.
- Abstract
- Magnetic Resonance Imaging (MRI) is a widely used noninvasive
clinical imaging modality. Unlike other medical imaging
tools, such as X-rays or computed tomography (CT), the advantage
of MRI is that it uses non-ionizing radiation. In addition, MRI can
provide images with multiple contrasts by using different pulse
sequences and protocols. However, image acquisition speed is
known to be a major drawback of MRI and is a limitation in various
MRI applications.
To address speed limitations in acquisition of multiple contrasts
images, we developed a new pulse sequence called Multi-contrast
sequence that enables simultaneous acquisition of the four contrasts
images, proton density (PD), T1-weighted, T2-weighted and
FLAIR images, with a single scan in less than 6 min. Multi-contrast
sequence is a combination of fast spin-echo (FSE) based imaging
pulse sequences with inversion recovery (IR) acquisition and non-
IR acquisition. From Multi-contrast sequence, two contrasts of
fluid-attenuated images, PD images, and T2-weighted images are
acquired at the same time and T1-weighted images are synthesized
from the obtained images. Compared to conventional imaging
sequences, the scan time is reduced by 50 %. Additionally, the new
method generates both T1 maps and T2 maps that can be used for
quantitative imaging.
To demonstrate the effectiveness of our approach, phantom and
in vivo experiments are performed. Then signal to noise ratio (SNR)
of images from the proposed sequence and from the conventional
sequences are compared. The method may have potentials as a
rapid evaluation tool for clinical scans.
- Language
- English
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