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Enantioselective Synthesis of Chiral Pyrrolidine-Fused Piperazine Derivatives via Diaza-Cope Rearrangement
DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | 김병문 | - |
dc.contributor.author | 송명종 | - |
dc.date.accessioned | 2017-10-31T08:34:39Z | - |
dc.date.available | 2017-10-31T08:34:39Z | - |
dc.date.issued | 2017-08 | - |
dc.identifier.other | 000000145040 | - |
dc.identifier.uri | https://hdl.handle.net/10371/138104 | - |
dc.description | 학위논문 (석사)-- 서울대학교 대학원 자연과학대학 화학부, 2017. 8. 김병문. | - |
dc.description.abstract | Piperazinopyrrolidine and pyrrolidinone derivatives represent one important class of natural products and pharmaceutical agents, which often display interesting biological activities. In this study, a highly efficient synthetic method was developed for the construction of enantiomerically pure chiral piperazinopyrrolidine derivatives via diaza-Cope rearrangement (DCR). This protocol can provide a new approach for the asymetric syntheses of some biologically relevant products possessing piperazinopyrrolidine moiety. | - |
dc.description.tableofcontents | 1. Introduction 1
2. Results & Discussion 3 3. Conclusion 5 4. Experimental Section 6 5. References 40 | - |
dc.format | application/pdf | - |
dc.format.extent | 4747725 bytes | - |
dc.format.medium | application/pdf | - |
dc.language.iso | en | - |
dc.publisher | 서울대학교 대학원 | - |
dc.subject | piperazine | - |
dc.subject | chiral compound | - |
dc.subject | diamine | - |
dc.subject | diaza-cope rearrangement | - |
dc.subject.ddc | 540 | - |
dc.title | Enantioselective Synthesis of Chiral Pyrrolidine-Fused Piperazine Derivatives via Diaza-Cope Rearrangement | - |
dc.type | Thesis | - |
dc.description.degree | Master | - |
dc.contributor.affiliation | 자연과학대학 화학부 | - |
dc.date.awarded | 2017-08 | - |
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