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Transglycosylation of gallic acid by using Leuconostoc glucansucrase and its characterization as a functional cosmetic agent
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Nam, Seung-Hee | - |
dc.contributor.author | Park, Jeongjin | - |
dc.contributor.author | Jun, Woojin | - |
dc.contributor.author | Kim, Doman | - |
dc.contributor.author | Ko, Jin-A | - |
dc.contributor.author | Abd El-Aty, A. M. | - |
dc.contributor.author | Choi, Jin Young | - |
dc.contributor.author | Kim, Do-Ik | - |
dc.contributor.author | Yang, Kwang-Yeol | - |
dc.date.accessioned | 2017-12-26T01:50:59Z | - |
dc.date.available | 2017-12-26T10:52:03Z | - |
dc.date.issued | 2017-12-22 | - |
dc.identifier.citation | AMB Express, 22;7(1):224 | ko_KR |
dc.identifier.issn | 2191-0855 | - |
dc.identifier.uri | https://hdl.handle.net/10371/138461 | - |
dc.description.abstract | Abstract
Gallic acid glycoside was enzymatically synthesized by using dextransucrase and sucrose from gallic acid. After purification by butanol partitioning and preparative HPLC, gallic acid glucoside was detected at m/z 355 (C13, H16, O10, Na)+ by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. The yield of gallic acid glucoside was found to be 35.7% (114mM) by response surface methodology using a reaction mixture of 319mM gallic acid, 355mM sucrose, and 930mU/mL dextransucrase. The gallic acid glucoside obtained showed 31% higher anti-lipid peroxidation and stronger inhibition (Ki=1.23mM) against tyrosinase than that shown by gallic acid (Ki=1.98mM). In UVB-irradiated human fibroblast cells, gallic acid glucoside lowered matrix metalloproteinase-1 levels and increased the collagen content, which was indicative of a stronger anti-aging effect than that of gallic acid or arbutin. These results indicated that gallic acid glucoside is likely a superior cosmetic ingredient with skin-whitening and anti-aging functions. | ko_KR |
dc.description.sponsorship | This study was supported by Basic Science Research Program through the National Research Foundation of Korea funded by the Ministry of Education (NRF-2016R1D1A1B03936148), Republic of Korea. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | Springer Open | ko_KR |
dc.subject | Leuconostoc mesenteroides | ko_KR |
dc.subject | Dextransucrase | ko_KR |
dc.subject | Gallic acid | ko_KR |
dc.subject | Glucosylation | ko_KR |
dc.subject | Whitening efect | ko_KR |
dc.subject | Anti-aging efect | ko_KR |
dc.title | Transglycosylation of gallic acid by using Leuconostoc glucansucrase and its characterization as a functional cosmetic agent | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 남승희 | - |
dc.contributor.AlternativeAuthor | 박정진 | - |
dc.contributor.AlternativeAuthor | 전우진 | - |
dc.contributor.AlternativeAuthor | 김도만 | - |
dc.contributor.AlternativeAuthor | 고진아 | - |
dc.contributor.AlternativeAuthor | 최진영 | - |
dc.contributor.AlternativeAuthor | 김도익 | - |
dc.contributor.AlternativeAuthor | 양광열 | - |
dc.identifier.doi | 10.1186/s13568-017-0523-x | - |
dc.language.rfc3066 | en | - |
dc.rights.holder | The Author(s) | - |
dc.date.updated | 2017-12-24T04:20:23Z | - |
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