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The role of nuclear factor I-C in tooth and bone development
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Cited 12 time in Scopus
- Authors
- Issue Date
- 2017-04
- Publisher
- 대한구강악안면외과학회
- Citation
- 대한구강악안면외과학회지, Vol.43 No.2, pp.63-69
- Abstract
- Nuclear factor I-C (NFI-C) plays a pivotal role in various cellular processes such as odontoblast and osteoblast differentiation. Nfic-deficient mice showed abnormal tooth and bone formation. The transplantation of Nfic-expressing mouse bone marrow stromal cells rescued the impaired bone formation in Nfic(-/-) mice. Studies suggest that NFI-C regulate osteogenesis and dentinogenesis in concert with several factors including transforming growth factor-beta 1, Kruppel-like factor 4, and beta-catenin. This review will focus on the function of NFI-C during tooth and bone formation and on the relevant pathways that involve NFI-C.
- ISSN
- 2234-7550
- Language
- English
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