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Structure Elucidation of Novel Compounds Bearing a Spiro-β-lactone-γ-lactam Ring Produced by Brevibacillus sp. Isolated from Dung Beetles Excretion : 소똥풍뎅이 분비물에서 분리된 Brevibacillus sp. 이 생산하는Spiro-β-lactone-γ-lactam ring 을 포함하는 신규 물질의 구조 규명
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.advisor | 오동찬 | - |
| dc.contributor.author | 우동희 | - |
| dc.date.accessioned | 2018-05-29T04:43:55Z | - |
| dc.date.available | 2021-04-13T01:25:35Z | - |
| dc.date.issued | 2018-02 | - |
| dc.identifier.other | 000000150726 | - |
| dc.identifier.uri | https://hdl.handle.net/10371/142236 | - |
| dc.description | 학위논문 (석사)-- 서울대학교 대학원 : 약학대학 약학과, 2018. 2. 오동찬. | - |
| dc.description.abstract | A Brevibacillus strain PTH23, which displayed inhibitory activity against bacteria, was isolated from dung beetles (Onthophagus lenzii) excretion. LC/MS analysis of the culture revealed that this bacterial strain produces three new spiro-β-lactone-γ-lactams, brevicillaenes A-C (1-3). The planar structures of these compounds were elucidated by spectroscopic analysis of 1D and 2D NMR, MS, and UV data. The absolute configurations of brevicillaenes A-C (1-3) were determined by the combination of chemical derivatizations, J-based configuration analysis, and quantum mechanics-based computational analysis. | - |
| dc.description.tableofcontents | Introduction 1
Results and discussion 3 Experimental section 16 References 25 Abstract in Korean 45 | - |
| dc.format | application/pdf | - |
| dc.format.extent | 5917013 bytes | - |
| dc.format.medium | application/pdf | - |
| dc.language.iso | en | - |
| dc.publisher | 서울대학교 대학원 | - |
| dc.subject | insect-associated bacteria | - |
| dc.subject | structure determination | - |
| dc.subject | spiro-β-lactone-γ-lactam | - |
| dc.subject.ddc | 615 | - |
| dc.title | Structure Elucidation of Novel Compounds Bearing a Spiro-β-lactone-γ-lactam Ring Produced by Brevibacillus sp. Isolated from Dung Beetles Excretion | - |
| dc.title.alternative | 소똥풍뎅이 분비물에서 분리된 Brevibacillus sp. 이 생산하는Spiro-β-lactone-γ-lactam ring 을 포함하는 신규 물질의 구조 규명 | - |
| dc.type | Thesis | - |
| dc.contributor.AlternativeAuthor | Donghee Woo | - |
| dc.description.degree | Master | - |
| dc.contributor.affiliation | 약학대학 약학과 | - |
| dc.date.awarded | 2018-02 | - |
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