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Effects of lifetime cumulative ginseng intake on cognitive function in late life
DC Field | Value | Language |
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dc.contributor.author | Lho, Silvia Kyungjin | - |
dc.contributor.author | Kim, Tae Hui | - |
dc.contributor.author | Kwak, Kyung Phil | - |
dc.contributor.author | Kim, Kayoung | - |
dc.contributor.author | Kim, Bong Jo | - |
dc.contributor.author | Kim, Shin Gyeom | - |
dc.contributor.author | Kim, Jeong Lan | - |
dc.contributor.author | Kim, Tae Hyun | - |
dc.contributor.author | Moon, Seok Woo | - |
dc.contributor.author | Park, Jae Young | - |
dc.contributor.author | Park, Joon Hyuk | - |
dc.contributor.author | Byun, Seonjeong | - |
dc.contributor.author | Suh, Seung Wan | - |
dc.contributor.author | Seo, Ji Young | - |
dc.contributor.author | So, Yoonseop | - |
dc.contributor.author | Ryu, Seung-Ho | - |
dc.contributor.author | Youn, Jong Chul | - |
dc.contributor.author | Lee, Kyoung Hwan | - |
dc.contributor.author | Lee, Dong Young | - |
dc.contributor.author | Lee, Dong Woo | - |
dc.contributor.author | Lee, Seok Bum | - |
dc.contributor.author | Lee, Jung Jae | - |
dc.contributor.author | Lee, Ju Ri | - |
dc.contributor.author | Jeong, Hyeon | - |
dc.contributor.author | Jeong, Hyun-Ghang | - |
dc.contributor.author | Jhoo, Jin Hyeong | - |
dc.contributor.author | Han, Kyuhee | - |
dc.contributor.author | Hong, Jong Woo | - |
dc.contributor.author | Han, Ji Won | - |
dc.contributor.author | Kim, Ki Woong | - |
dc.date.accessioned | 2018-07-23T07:58:11Z | - |
dc.date.available | 2018-07-23T16:59:45Z | - |
dc.date.issued | 2018-05-24 | - |
dc.identifier.citation | Alzheimer's Research & Therapy, 10(1):50 | ko_KR |
dc.identifier.issn | 1758-9193 | - |
dc.identifier.uri | https://hdl.handle.net/10371/142748 | - |
dc.description.abstract | Background
We investigated the effects of lifetime cumulative ginseng intake on cognitive function in a community-dwelling population-based prospective cohort of Korean elders. Methods Community-dwelling elders (N = 6422; mean age = 70.2 ± 6.9years, education = 8.0 ± 5.3years, female = 56.8%) from the Korean Longitudinal Study on Cognitive Aging and Dementia were included. Among them, 3918 participants (61.0%) completed the 2-year and 4-year follow-up evaluations. Subjects were categorized according to cumulative ginseng intake at baseline evaluation; no use group, low use (< 5years) group, and high use (≥ 5years) group. One-way analysis of covariance (ANCOVA) was conducted to compare the impact of cumulative ginseng intake on baseline Consortium to Establish a Registry for Alzheimers Disease Assessment Packet neuropsychological battery total score (CERAD total score) and Mini-Mental State Examination (MMSE) score among the three groups while adjusting for potential covariates. A repeated-measures ANCOVA was performed to investigate the impacts on the changes in CERAD total scores and MMSE scores during the 4years of follow-up. Results The high use group showed higher CERAD total scores compared to the no use group after controlling for age, sex, education years, socioeconomic status, smoking, alcohol intake, presence of hypertension, stroke history, Geriatric Depression Scale, Cumulative Illness Rating Scale, and presence of the APOE e4 allele (F(2, 4762) = 3.978, p = 0.019). The changes of CERAD total score for 2 or 4years of follow-up did not differ according to the use of ginseng. Conclusions Cumulative ginseng use for longer than 5years may be beneficial to cognitive function in late life. | ko_KR |
dc.description.sponsorship | This study was supported by a grant from the Korean Health Technology R&D Project, Ministry of Health and Welfare, Republic of Korea (grant no. HI09C1379 [A092077]). | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | BioMed Central | ko_KR |
dc.subject | Ginseng | ko_KR |
dc.subject | Panax | ko_KR |
dc.subject | Aged | ko_KR |
dc.subject | Cognition | ko_KR |
dc.subject | Cohort studies | ko_KR |
dc.subject | Longitudinal studies | ko_KR |
dc.title | Effects of lifetime cumulative ginseng intake on cognitive function in late life | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 로경진 | - |
dc.contributor.AlternativeAuthor | 김태희 | - |
dc.contributor.AlternativeAuthor | 곽경필 | - |
dc.contributor.AlternativeAuthor | 김가영 | - |
dc.contributor.AlternativeAuthor | 김봉조 | - |
dc.contributor.AlternativeAuthor | 김신겸 | - |
dc.contributor.AlternativeAuthor | 김정란 | - |
dc.contributor.AlternativeAuthor | 김태현 | - |
dc.contributor.AlternativeAuthor | 문석우 | - |
dc.contributor.AlternativeAuthor | 박재영 | - |
dc.contributor.AlternativeAuthor | 박준혁 | - |
dc.contributor.AlternativeAuthor | 변선정 | - |
dc.contributor.AlternativeAuthor | 서승완 | - |
dc.contributor.AlternativeAuthor | 서지영 | - |
dc.contributor.AlternativeAuthor | 소윤섭 | - |
dc.contributor.AlternativeAuthor | 류승호 | - |
dc.contributor.AlternativeAuthor | 윤종철 | - |
dc.contributor.AlternativeAuthor | 이경환 | - |
dc.contributor.AlternativeAuthor | 이동영 | - |
dc.contributor.AlternativeAuthor | 이동우 | - |
dc.contributor.AlternativeAuthor | 이석범 | - |
dc.contributor.AlternativeAuthor | 이정재 | - |
dc.contributor.AlternativeAuthor | 이주리 | - |
dc.contributor.AlternativeAuthor | 정현 | - |
dc.contributor.AlternativeAuthor | 정현강 | - |
dc.contributor.AlternativeAuthor | 주진형 | - |
dc.contributor.AlternativeAuthor | 한규희 | - |
dc.contributor.AlternativeAuthor | 홍종우 | - |
dc.contributor.AlternativeAuthor | 한지원 | - |
dc.contributor.AlternativeAuthor | 김기웅 | - |
dc.identifier.doi | 10.1186/s13195-018-0380-0 | - |
dc.language.rfc3066 | en | - |
dc.rights.holder | The Author(s). | - |
dc.date.updated | 2018-05-27T03:36:57Z | - |
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