Browse

IgG4-related ophthalmic disease involving extraocular muscles: case series

Cited 5 time in Web of Science Cited 6 time in Scopus
Issue Date
2018-07-03
Publisher
BioMed Central
Citation
BMC Ophthalmology, 18(1):162
Keywords
StrabismusIgG4-related ophthalmic diseaseExtraocular muscleImaging findingsCase report
Abstract
Background
To elucidate the clinical features of strabismus associated with IgG4-related ophthalmic disease (IgG4-ROD).

Case summary
All of the four patients with IgG4-ROD showed marked enlargement of the extraocular muscles, however, two patients showed orthotropia with full ductions and versions. One patient showed a small angle of exotropia and hypertropia of less than 5 prism diopters. One remaining patient showed orthotropia, full ductions and versions despite marked enlargement of the extraocular muscles, then developed hypertropia up to 35 prism diopters with activation of inflammation, which promptly improved after treatment with oral steroids.

Conclusions
IgG4-ROD usually shows normal ocular motility despite extraocular muscle enlargement, which is the key distinguishing feature from other orbital inflammatory diseases. Active flare-up with increased serum IgG4 levels may produce a large angle of eye deviation, but mostly respond well to steroid treatment.
ISSN
1471-2415
Language
English
URI
https://hdl.handle.net/10371/142936
DOI
https://doi.org/10.1186/s12886-018-0819-x
Files in This Item:
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Radiology (영상의학전공)Journal Papers (저널논문_영상의학전공)
College of Medicine/School of Medicine (의과대학/대학원)Ophthalmology (안과학전공)Journal Papers (저널논문_안과학전공)
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse