S-Space College of Engineering/Engineering Practice School (공과대학/대학원) Dept. of Electrical and Computer Engineering (전기·정보공학부) Theses (Master's Degree_전기·정보공학부)
Importance of reference in QSM and a new differential ROI reference method
정량적 자화율 영상 매핑 기법에서 기준 영역의 중요성과 새로운 차등영역 기준 방법
- 이종호 (B)
- 공과대학 전기·정보공학부
- Issue Date
- 서울대학교 대학원
- 학위논문 (석사)-- 서울대학교 대학원 : 공과대학 전기·정보공학부, 2018. 8. 이종호 (B).
- In this study, we developed a computer simulation to demonstrate the importance of reference in QSM. The results show that QSM values were not only dependent on the brain slab width but also dependent on brain mask size. Furthermore, when the background removal was not perfect, this difference was more dependent on this condition. Only when the data are referenced using a neighboring region, the QSM results provide correct susceptibility difference values regardless of these conditions. Also, we demonstrate this new approach for a Parkinsons disease (PD) patient study. In contrast to the previous QSM study, the use of differential ROI reference avoids the assumption of equal susceptibility in the reference between groups in group comparison and directly reports the susceptibility difference between two ROIs, no longer allowing ambiguity in interpretation.