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C-methylated flavonoid glycosides from Pentarhizidium orientale rhizomes and their inhibitory effects on the H1N1 influenza virus
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Huh, Jungmoo | - |
| dc.contributor.author | Ha, Thi Kim Quy | - |
| dc.contributor.author | Kang, Kyo Bin | - |
| dc.contributor.author | Kim, Ki Hyun | - |
| dc.contributor.author | Oh, Won Keun | - |
| dc.contributor.author | Kim, Jinwoong | - |
| dc.contributor.author | Sung, Sang Hyun | - |
| dc.creator | 오원근 | - |
| dc.date.accessioned | 2019-04-24T08:35:24Z | - |
| dc.date.available | 2020-04-05T08:35:24Z | - |
| dc.date.created | 2018-02-06 | - |
| dc.date.created | 2018-02-06 | - |
| dc.date.created | 2018-02-06 | - |
| dc.date.created | 2018-02-06 | - |
| dc.date.issued | 2017-10 | - |
| dc.identifier.citation | Journal of Natural Products, Vol.80 No.10, pp.2818-2824 | - |
| dc.identifier.issn | 0163-3864 | - |
| dc.identifier.uri | https://hdl.handle.net/10371/148290 | - |
| dc.description.abstract | Thirteen C-methylated flavonoid glycosides (1-13), along with 15 previously known flavonoids (14-28), were isolated from rhizomes of Pentarhizidium orientale. Among these compounds, matteuorienates D-K (1-8) were obtained as analogues of matteuorienates A-C (14-16), which contain a characteristic 3-hydroxy-3-methylglutaryl (HMG) moiety. The structures of 1-13 were characterized by spectroscopic analysis and chemical derivatization. The isolates were evaluated for their antiviral activities against influenza virus (H1N1), with compounds 21, 22, 23, 25, and 26 showing inhibitory effects (IC50 of 23.9-30.3 mu M) against neuraminidases. | - |
| dc.language | 영어 | - |
| dc.language.iso | en | en |
| dc.publisher | American Chemical Society | - |
| dc.title | C-methylated flavonoid glycosides from Pentarhizidium orientale rhizomes and their inhibitory effects on the H1N1 influenza virus | - |
| dc.type | Article | - |
| dc.identifier.doi | 10.1021/acs.jnatprod.7b00677 | - |
| dc.citation.journaltitle | Journal of Natural Products | - |
| dc.identifier.wosid | 000414234400029 | - |
| dc.identifier.scopusid | 2-s2.0-85032585774 | - |
| dc.description.srnd | OAIID:RECH_ACHV_DSTSH_NO:T201723916 | - |
| dc.description.srnd | RECH_ACHV_FG:RR00200001 | - |
| dc.description.srnd | ADJUST_YN: | - |
| dc.description.srnd | EMP_ID:A079209 | - |
| dc.description.srnd | CITE_RATE:3.885 | - |
| dc.description.srnd | DEPT_NM:약학과 | - |
| dc.description.srnd | EMAIL:wkoh1@snu.ac.kr | - |
| dc.description.srnd | SCOPUS_YN:Y | - |
| dc.citation.endpage | 2824 | - |
| dc.citation.number | 10 | - |
| dc.citation.startpage | 2818 | - |
| dc.citation.volume | 80 | - |
| dc.description.isOpenAccess | N | - |
| dc.contributor.affiliatedAuthor | Oh, Won Keun | - |
| dc.contributor.affiliatedAuthor | Kim, Jinwoong | - |
| dc.contributor.affiliatedAuthor | Sung, Sang Hyun | - |
| dc.identifier.srnd | T201723916 | - |
| dc.type.docType | Article | - |
| dc.description.journalClass | 1 | - |
| dc.subject.keywordPlus | ALDOSE REDUCTASE INHIBITORS | - |
| dc.subject.keywordPlus | MATTEUCCIA-ORIENTALIS | - |
| dc.subject.keywordPlus | ABSOLUTE-CONFIGURATION | - |
| dc.subject.keywordPlus | CLEISTOCALYX-OPERCULATUS | - |
| dc.subject.keywordPlus | TREV | - |
| dc.subject.keywordPlus | NEURAMINIDASE | - |
| dc.subject.keywordPlus | CONSTITUENTS | - |
| dc.subject.keywordPlus | DERIVATIVES | - |
| dc.subject.keywordPlus | LEAVES | - |
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