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The F-box protein FKF1 inhibits dimerization of COP1 in the control of photoperiodic flowering
DC Field | Value | Language |
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dc.contributor.author | Lee, Byoung-Doo | - |
dc.contributor.author | Kim, Mi Ri | - |
dc.contributor.author | Kang, Min-Young | - |
dc.contributor.author | Cha, Joon-Yung | - |
dc.contributor.author | Han, Su-Hyun | - |
dc.contributor.author | Nawkar, Ganesh M. | - |
dc.contributor.author | Sakuraba, Yasuhito | - |
dc.contributor.author | Lee, Sang Yeol | - |
dc.contributor.author | Imaizumi, Takato | - |
dc.contributor.author | McClung, C. Robertson | - |
dc.contributor.author | Kim, Woe-Yeon | - |
dc.contributor.author | Paek, Nam-Chon | - |
dc.creator | 백남천 | - |
dc.date.accessioned | 2019-04-25T00:13:30Z | - |
dc.date.available | 2020-04-05T00:13:30Z | - |
dc.date.created | 2018-03-08 | - |
dc.date.issued | 2017-12 | - |
dc.identifier.citation | Nature Communications, Vol.8, p. 2259 | - |
dc.identifier.issn | 2041-1723 | - |
dc.identifier.uri | https://hdl.handle.net/10371/148909 | - |
dc.description.abstract | In Arabidopsis thaliana, CONSTANS (CO) plays an essential role in the regulation of photoperiodic flowering under long-day conditions. CO protein is stable only in the afternoon of long days, when it induces the expression of FLOWERING LOCUS T (FT), which promotes flowering. The blue-light photoreceptor FLAVIN-BINDING, KELCH REPEAT, F-BOX1 (FKF1) interacts with CO and stabilizes it by an unknown mechanism. Here, we provide genetic and biochemical evidence that FKF1 inhibits CONSTITUTIVE PHOTOMORPHOGENIC1 (COP1)-dependent CO degradation. Light-activated FKF1 has no apparent effect on COP1 stability but can interact with and negatively regulate COP1. We show that FKF1 can inhibit COP1 homo-dimerization. Mutation of the coiled-coil domain in COP1, which prevents dimer formation, impairs COP1 function in coordinating flowering time. Based on these results, we propose a model whereby the light-and day length-dependent interaction between FKF1 and COP1 controls CO stability to regulate flowering time. | - |
dc.language | 영어 | - |
dc.language.iso | en | en |
dc.publisher | Nature Publishing Group | - |
dc.title | The F-box protein FKF1 inhibits dimerization of COP1 in the control of photoperiodic flowering | - |
dc.type | Article | - |
dc.identifier.doi | 10.1038/s41467-017-02476-2 | - |
dc.citation.journaltitle | Nature Communications | - |
dc.identifier.wosid | 000418570600004 | - |
dc.identifier.scopusid | 2-s2.0-85039159643 | - |
dc.description.srnd | OAIID:RECH_ACHV_DSTSH_NO:T201725551 | - |
dc.description.srnd | RECH_ACHV_FG:RR00200001 | - |
dc.description.srnd | ADJUST_YN: | - |
dc.description.srnd | EMP_ID:A002118 | - |
dc.description.srnd | CITE_RATE:12.353 | - |
dc.description.srnd | FILENAME:Lee_et_al-2017-Nature_Communications.pdf | - |
dc.description.srnd | DEPT_NM:식물생산과학부 | - |
dc.description.srnd | EMAIL:ncpaek@snu.ac.kr | - |
dc.description.srnd | SCOPUS_YN:Y | - |
dc.description.srnd | FILEURL:https://srnd.snu.ac.kr/eXrepEIR/fws/file/98f91bf7-80d1-43c7-b22f-504ca863ead0/link | - |
dc.citation.startpage | 2259 | - |
dc.citation.volume | 8 | - |
dc.description.isOpenAccess | Y | - |
dc.contributor.affiliatedAuthor | Paek, Nam-Chon | - |
dc.identifier.srnd | T201725551 | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | LOCUS-T | - |
dc.subject.keywordPlus | PLANT PHOTOMORPHOGENESIS | - |
dc.subject.keywordPlus | CIRCADIAN CLOCK | - |
dc.subject.keywordPlus | LIGHT CONTROL | - |
dc.subject.keywordPlus | CONSTANS | - |
dc.subject.keywordPlus | REPRESSOR | - |
dc.subject.keywordPlus | TIME | - |
dc.subject.keywordPlus | GENE | - |
dc.subject.keywordPlus | NUCLEAR | - |
dc.subject.keywordPlus | LOCALIZATION | - |
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