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The robustness of T-2 value as a trabecular structural index at multiple spatial resolutions of 7 Tesla MRI
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Dongkyu | - |
dc.contributor.author | Song, Youngkyu | - |
dc.contributor.author | Park, Bumwoo | - |
dc.contributor.author | Cho, H. P. | - |
dc.contributor.author | Yeom, Jin Sup | - |
dc.contributor.author | Cho, Gyunggoo | - |
dc.contributor.author | Cho, HyungJoon | - |
dc.creator | 염진섭 | - |
dc.date.accessioned | 2019-04-25T01:51:38Z | - |
dc.date.available | 2020-04-05T01:51:38Z | - |
dc.date.created | 2018-12-20 | - |
dc.date.created | 2018-12-20 | - |
dc.date.issued | 2018-11 | - |
dc.identifier.citation | Magnetic Resonance in Medicine, Vol.80 No.5, pp.1949-1961 | - |
dc.identifier.issn | 0740-3194 | - |
dc.identifier.uri | https://hdl.handle.net/10371/149732 | - |
dc.description.abstract | Purpose: To evaluate the robustness of MR transverse relaxation times of trabecular bone from spin-echo and gradient-echo acquisitions at multiple spatial resolutions of 7 T. Methods: The effects of MRI resolutions to T-2 and T-2* trabecular bone were numerically evaluated by Monte Carlo simulations. T-2, T-2* and trabecular structural indices from multislice multi-echo and UTE acquisitions were measured in defatted human distal femoral condyles on a 7 T scanner. Reference structural indices were extracted from high-resolution microcomputed tomography images. For bovine knee trabecular samples with intact bone marrow, T-2 and T-2* were measured by degrading spatial resolutions on a 7 T system. Results: In the defatted trabecular experiment, both T-2 and T-2* values showed strong (vertical bar r vertical bar> 0.80) correlations with trabecular spacing and number, at a high spatial resolution of 125 mu m(3). The correlations for MR image-segmentation-olutions of 250 and 500 mu m(3). The correlations for T-2* rapidly dropped (vertical bar r vertical bar< 0.50) at a spatial resolution of 500 mu m(3), whereas those for T-2* remained consistently high (vertical bar r vertical bar> 0.85). In the bovine trabecular experiments with intact marrow, low- resolution (approximately 1 mm(3), 2 minutes) T-2 values did not shorten (vertical bar r vertical bar> 0.95 with respect to approximately 0.4mm(3), 11 minutes) and maintained consistent correlations (vertical bar r vertical bar > 0.70) with respect to trabecular spacing (turbo spin echo, 22.5 minutes). Conclusion: T-2 measurements of trabeculae at 7 T are robust with degrading spatial resolution and may be preferable in assessing trabecular spacing index with reduced scan time, when high-resolution 3D micro-MRI is difficult to obtain. | - |
dc.language | 영어 | - |
dc.language.iso | en | en |
dc.publisher | John Wiley & Sons Inc. | - |
dc.title | The robustness of T-2 value as a trabecular structural index at multiple spatial resolutions of 7 Tesla MRI | - |
dc.type | Article | - |
dc.identifier.doi | 10.1002/mrm.27202 | - |
dc.citation.journaltitle | Magnetic Resonance in Medicine | - |
dc.identifier.wosid | 000448872700016 | - |
dc.identifier.scopusid | 2-s2.0-85045415553 | - |
dc.description.srnd | OAIID:RECH_ACHV_DSTSH_NO:T201809398 | - |
dc.description.srnd | RECH_ACHV_FG:RR00200001 | - |
dc.description.srnd | ADJUST_YN: | - |
dc.description.srnd | EMP_ID:A079510 | - |
dc.description.srnd | CITE_RATE:4.082 | - |
dc.description.srnd | FILENAME:The robustness of T2 value as a trabecular structural index.pdf | - |
dc.description.srnd | DEPT_NM:의학과 | - |
dc.description.srnd | EMAIL:spine@snu.ac.kr | - |
dc.description.srnd | SCOPUS_YN:Y | - |
dc.description.srnd | FILEURL:https://srnd.snu.ac.kr/eXrepEIR/fws/file/2a3eccd3-41af-44d9-a0ca-8457695aa65e/link | - |
dc.citation.endpage | 1961 | - |
dc.citation.number | 5 | - |
dc.citation.startpage | 1949 | - |
dc.citation.volume | 80 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Yeom, Jin Sup | - |
dc.identifier.srnd | T201809398 | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | ARTICULAR-CARTILAGE | - |
dc.subject.keywordPlus | BONE-STRUCTURE | - |
dc.subject.keywordPlus | MAGNETIC-FIELD | - |
dc.subject.keywordPlus | 3 T | - |
dc.subject.keywordPlus | OSTEOPOROSIS | - |
dc.subject.keywordPlus | INTERRELATIONSHIP | - |
dc.subject.keywordPlus | MICROARCHITECTURE | - |
dc.subject.keywordPlus | INTERFEROMETRY | - |
dc.subject.keywordPlus | RELAXATION | - |
dc.subject.keywordPlus | PARAMETERS | - |
dc.subject.keywordAuthor | magnetic resonance relaxations | - |
dc.subject.keywordAuthor | magnetic resonance spatial resolution | - |
dc.subject.keywordAuthor | trabecular structure | - |
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