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Comparative study of induction of labor in nulliparous women with premature rupture of membranes at term compared to those with intact membranes: duration of labor and mode of delivery

Cited 17 time in Web of Science Cited 18 time in Scopus
Authors
Park, Kyo Hoon; Hong, Joon-Seok; Ko, Ji Kyung; Cho, Yong Kyoon; Lee, Chul Min; Choi, Hoon; Kim, Bok Rin
Issue Date
2006-09-21
Publisher
Wiley-Blackwell
Citation
J Obstet Gynaecol Res. 2006 Oct;32(5):482-8.
Keywords
AdultCesarean Section/statistics & numerical dataDelivery, Obstetric/*methodsFemaleFetal MacrosomiaFetal Membranes, Premature Rupture/*therapyHumans*Labor, InducedLabor, Obstetric/*physiologyLogistic ModelsParityPregnancyRetrospective StudiesTime Factors
Abstract
AIM: To evaluate the effect of premature rupture of membranes (PROM) at term on the duration of labor and mode of delivery in comparison with intact membranes in nulliparous women with an unfavorable cervix whose labor was induced. METHODS: This retrospective cohort study included all term nulliparous women with an unfavorable cervix requiring labor induction over a 2-year period. Prostaglandin E(2) (dinoprostone) and oxytocin were used for labor induction. Criteria for enrolment included (i) singleton pregnancy; (ii) term nulliparous women; or (iii) Bishop score below 6. Statistics were analyzed with Student's t-test, chi(2)-test, Fisher's exact test, and multiple logistic regression. RESULTS: Our study subjects were 82 women whose labor was induced for PROM and 219 women with intact membranes whose labor was induced for social or fetal reasons. The mean durations of active phase of labor were not significantly different between women with PROM and those with intact membranes. However, the women with PROM had a significantly longer mean duration of second stage and a higher rate of cesarean delivery for failure to progress than those with intact membranes. Multiple logistic regression demonstrated that only PROM and fetal macrosomia were significantly associated with an increased risk of cesarean delivery for failure to progress after other confounding variables were adjusted. CONCLUSIONS: Labor induction for PROM at term in nulliparous women with an unfavorable cervix is associated with longer duration of the second stage and a higher risk of cesarean delivery for failure to progress in comparison to those with intact membranes.
ISSN
1341-8076 (Print)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16984515

http://hdl.handle.net/10371/15476
DOI
https://doi.org/10.1111/j.1447-0756.2006.00443.x
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Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Obstetrics & Gynecology (산부인과전공)Journal Papers (저널논문_산부인과학전공)
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