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Bahamaolides A-B, Novel antifungal-macrocyclic lactones from marine actinomycete, streptomyces sp. CNQ343
DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | 오동찬 | - |
dc.contributor.author | 김동규 | - |
dc.date.accessioned | 2019-06-25T16:03:13Z | - |
dc.date.available | 2019-06-25T16:03:13Z | - |
dc.date.issued | 2012-02 | - |
dc.identifier.other | 000000000481 | - |
dc.identifier.uri | https://hdl.handle.net/10371/155169 | - |
dc.identifier.uri | http://dcollection.snu.ac.kr/jsp/common/DcLoOrgPer.jsp?sItemId=000000000481 | - |
dc.description | 학위논문 (석사)-- 서울대학교 대학원 : 약학과, 2012. 2. 오동찬. | - |
dc.description.abstract | Two new 36-membered macrocyclic lactones, designated to be bahamaolides A and B, were isolated from the culture broth of the marine actinomycete Streptomyces sp. derived from a sediment sample collected at North Cat Bay in the Bahamas. The planar structures of bahamaolides A-B, bearing a hexaenone and nine consecutive skipped hydroxy groups, were determined by a combination of 1D and 2D NMR, mass, IR, and UV spectra. The absolute configurations of these compounds were established based on the multiple-step chemical reactions and spectroscopic analysis. Bahamaolides displayed significant inhibitory activity against Candida albicans-isocitrate lyase. | - |
dc.format.extent | 68p | - |
dc.language.iso | eng | - |
dc.publisher | 서울대학교 대학원 | - |
dc.subject.ddc | 615 | - |
dc.title | Bahamaolides A-B, Novel antifungal-macrocyclic lactones from marine actinomycete, streptomyces sp. CNQ343 | - |
dc.type | Thesis | - |
dc.type | Dissertation | - |
dc.description.degree | Master | - |
dc.contributor.affiliation | 약학과 | - |
dc.date.awarded | 2012-02 | - |
dc.identifier.holdings | 000000000006▲000000000011▲000000000481▲ | - |
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