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Bahamaolides A-B, Novel antifungal-macrocyclic lactones from marine actinomycete, streptomyces sp. CNQ343

DC Field Value Language
dc.contributor.advisor오동찬-
dc.contributor.author김동규-
dc.date.accessioned2019-06-25T16:03:13Z-
dc.date.available2019-06-25T16:03:13Z-
dc.date.issued2012-02-
dc.identifier.other000000000481-
dc.identifier.urihttps://hdl.handle.net/10371/155169-
dc.identifier.urihttp://dcollection.snu.ac.kr/jsp/common/DcLoOrgPer.jsp?sItemId=000000000481-
dc.description학위논문 (석사)-- 서울대학교 대학원 : 약학과, 2012. 2. 오동찬.-
dc.description.abstractTwo new 36-membered macrocyclic lactones, designated to be bahamaolides A and B, were isolated from the culture broth of the marine actinomycete Streptomyces sp. derived from a sediment sample collected at North Cat Bay in the Bahamas. The planar structures of bahamaolides A-B, bearing a hexaenone and nine consecutive skipped hydroxy groups, were determined by a combination of 1D and 2D NMR, mass, IR, and UV spectra. The absolute configurations of these compounds were established based on the multiple-step chemical reactions and spectroscopic analysis. Bahamaolides displayed significant inhibitory activity against Candida albicans-isocitrate lyase.-
dc.format.extent68p-
dc.language.isoeng-
dc.publisher서울대학교 대학원-
dc.subject.ddc615-
dc.titleBahamaolides A-B, Novel antifungal-macrocyclic lactones from marine actinomycete, streptomyces sp. CNQ343-
dc.typeThesis-
dc.typeDissertation-
dc.description.degreeMaster-
dc.contributor.affiliation약학과-
dc.date.awarded2012-02-
dc.identifier.holdings000000000006▲000000000011▲000000000481▲-
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College of Pharmacy (약학대학)Dept. of Pharmacy (약학과)Theses (Master's Degree_약학과)
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