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Outcome of donors with a remnant liver volume of less than 35% after right hepatectomy
DC Field | Value | Language |
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dc.contributor.author | Cho, Jai Young | - |
dc.contributor.author | Suh, Kyung-Suk | - |
dc.contributor.author | Kwon, Choon Hyuck | - |
dc.contributor.author | Yi, Nam-Joon | - |
dc.contributor.author | Lee, Hwan Hyo | - |
dc.contributor.author | Park, Jean Wan | - |
dc.contributor.author | Lee, Kwang-Woong | - |
dc.contributor.author | Joh, Jae Won | - |
dc.contributor.author | Lee, Suk-Koo | - |
dc.contributor.author | Lee, Kuhn Uk | - |
dc.date.accessioned | 2009-11-25T23:51:53Z | - |
dc.date.available | 2009-11-25T23:51:53Z | - |
dc.date.issued | 2006-02-01 | - |
dc.identifier.citation | Liver Transpl. 2006 Feb;12(2):201-6 | en |
dc.identifier.issn | 1527-6465 (Print) | - |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16447201 | - |
dc.identifier.uri | https://hdl.handle.net/10371/15532 | - |
dc.description.abstract | To overcome the barrier of size match, right lobe graft has been widely used in living donor liver transplantation (LDLT). We assessed donor outcome, with a focus on remnant liver volume (RLV) after right hepatectomy based on the experiences of 2 LDLT centers, as a means of guiding the establishment of safe RLV limits for donor right hepatectomy. Between January 2002 and December 2003, a consecutive 146 liver donors who underwent right hepatectomy with at least 12 months of follow-up were enrolled in this study. Donors were grouped into 2 groups according to RLV: group 1 (n = 74), <35% (range, 26.9-34.9) and group 2 (n = 72), > or = 35% (35.0-46.8). No donors died or suffered a life-threatening complication. Mean peak serum postoperative aspartate aminotransferase (AST) and alanine aminotransferase (ALT) (IU/L) levels were 219.5 +/- 79.9 and 231.5 +/- 83.3 in group 1 and 210.3 +/- 81.6 and 225.8 +/- 93.0 in group 2 (P = 0.497 and 0.699), respectively. Mean peak serum total bilirubin (TB) (mg/dL) level in group 1 (3.4 +/- 1.6) was higher than in group 2 (2.8 +/- 1.4; P = 0.023). Overall 23 (15.8%) major morbidities, 10 in group 1 (13.5%) and 13 in group 2 (18.1%), occurred according to Clavien's system (P = 0.939). These included bleeding (n = 3 in group 1 and n = 6 in group 2; P = 0.282), ileus (n = 3 and 1; P = 0.324), biliary leakage (n = 4 and 4; P = 0.968), and pneumonia (n = 0 and 2; P = 0.149). Minor morbidities were also comparable in the 2 groups. In conclusion, the outcome of donors with an RLV of <35% was not different from that of donors with an RLV of > or = 35%, with the exception of transient cholestasis. Therefore, a remnant RLV of <35% does not appear to be a contraindication for right liver procurement in living donors. | en |
dc.language.iso | en | - |
dc.publisher | John Wiley & Sons | en |
dc.subject | Adolescent | en |
dc.subject | Adult | en |
dc.subject | Age Distribution | en |
dc.subject | Cohort Studies | en |
dc.subject | Female | en |
dc.subject | Follow-Up Studies | en |
dc.subject | Graft Rejection/prevention & control | en |
dc.subject | Hepatectomy/adverse effects/*methods | en |
dc.subject | Humans | en |
dc.subject | Incidence | en |
dc.subject | Liver Function Tests | en |
dc.subject | Liver Regeneration/*physiology | en |
dc.subject | Liver Transplantation/adverse effects/*methods | en |
dc.subject | Male | en |
dc.subject | Middle Aged | en |
dc.subject | Organ Preservation/methods | en |
dc.subject | Organ Size | en |
dc.subject | Postoperative Complications/*diagnosis/epidemiology | en |
dc.subject | Probability | en |
dc.subject | Risk Assessment | en |
dc.subject | Sex Distribution | en |
dc.subject | Living Donors | - |
dc.title | Outcome of donors with a remnant liver volume of less than 35% after right hepatectomy | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 조재영 | - |
dc.contributor.AlternativeAuthor | 서경석 | - |
dc.contributor.AlternativeAuthor | 권준혁 | - |
dc.contributor.AlternativeAuthor | 이남준 | - |
dc.contributor.AlternativeAuthor | 이환효 | - |
dc.contributor.AlternativeAuthor | 박진환 | - |
dc.contributor.AlternativeAuthor | 이광웅 | - |
dc.contributor.AlternativeAuthor | 조재원 | - |
dc.contributor.AlternativeAuthor | 이석구 | - |
dc.contributor.AlternativeAuthor | 이건욱 | - |
dc.identifier.doi | 10.1002/lt.20592 | - |
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