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Dissemination of SHV-12 and CTX-M-type extended-spectrum beta-lactamases among clinical isolates of Escherichia coli and Klebsiella pneumoniae and emergence of GES-3 in Korea
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ryoo, Nam Hee | - |
dc.contributor.author | Kim, Eui-Chong | - |
dc.contributor.author | Hong, Seong Geun | - |
dc.contributor.author | Park, Yeon Joon | - |
dc.contributor.author | Lee, Kyungwon | - |
dc.contributor.author | Bae, Il Kwon | - |
dc.contributor.author | Song, Eun Hyang | - |
dc.contributor.author | Jeong, Seok Hoon | - |
dc.date.accessioned | 2009-11-26T02:37:58Z | - |
dc.date.available | 2009-11-26T02:37:58Z | - |
dc.date.issued | 2005-09-06 | - |
dc.identifier.citation | J Antimicrob Chemother. 2005 Oct;56(4):698-702. Epub 2005 Sep 2. | en |
dc.identifier.issn | 0305-7453 (Print) | - |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16141280 | - |
dc.identifier.uri | https://hdl.handle.net/10371/15663 | - |
dc.description.abstract | OBJECTIVES: To assess the prevalence and genotypes of Ambler class A extended-spectrum beta-lactamases (ESBLs) in Korea. METHODS: Clinical isolates of Escherichia coli and Klebsiella pneumoniae collected from 12 Korean hospitals during February-July 2003 were evaluated. Antimicrobial susceptibilities were determined by disc diffusion and agar dilution methods, and the putative ESBL-producing strains were tested by the double-disc synergy method. Detection of genes encoding class A beta-lactamases was performed by PCR amplification, and the PCR products were subjected to direct sequencing. RESULTS: The double-disc synergy test showed positive results in 9.3% (23/246) of E. coli and 23.0% (55/239) of K. pneumoniae isolates. The most prevalent types of Ambler class A ESBLs in E. coli isolates were CTX-M-15 (n = 4) and CTX-M-3 (n = 3), and those in K. pneumoniae isolates were SHV-12 (n = 30) and CTX-M-3 (n = 13). Two isolates produced both SHV-12 and GES-3, simultaneously. CONCLUSIONS: CTX-M-type and/or SHV-12 ESBL-producing E. coli and K. pneumoniae isolates are spreading, and a GES-type ESBL has emerged in Korea. | en |
dc.language.iso | en | - |
dc.publisher | Oxford University Press | en |
dc.subject | Anti-Bacterial Agents/pharmacology | en |
dc.subject | Drug Resistance, Bacterial | en |
dc.subject | Escherichia coli Infections/epidemiology/*microbiology | en |
dc.subject | Hospitals | en |
dc.subject | Humans | en |
dc.subject | Klebsiella Infections/epidemiology/*microbiology | en |
dc.subject | Korea/epidemiology | en |
dc.subject | Escherichia coli/drug effects/*enzymology/genetics/isolation & purification | en |
dc.subject | Klebsiella pneumoniae/drug effects/*enzymology/genetics/isolation & purification | en |
dc.subject | Microbial Sensitivity Tests | en |
dc.subject | beta-Lactamases/*genetics | en |
dc.title | Dissemination of SHV-12 and CTX-M-type extended-spectrum beta-lactamases among clinical isolates of Escherichia coli and Klebsiella pneumoniae and emergence of GES-3 in Korea | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 류남희 | - |
dc.contributor.AlternativeAuthor | 김의종 | - |
dc.contributor.AlternativeAuthor | 홍성근 | - |
dc.contributor.AlternativeAuthor | 박연준 | - |
dc.contributor.AlternativeAuthor | 이경원 | - |
dc.contributor.AlternativeAuthor | 배일권 | - |
dc.contributor.AlternativeAuthor | 송은향 | - |
dc.contributor.AlternativeAuthor | 정석훈 | - |
dc.identifier.doi | 10.1093/jac/dki324 | - |
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