Publications

Detailed Information

Aphasia following striatocapsular infarction may be explained by concomitant small cortical infarct on diffusion-weighted imaging

Cited 3 time in Web of Science Cited 4 time in Scopus
Authors

Han, Moon-Ku; Kang, Dong-Wha; Jeong, Sang-Wuk; Roh, Jae-Kyu

Issue Date
2005-02-11
Publisher
Karger
Citation
Cerebrovasc Dis. 2005;19(4):220-4. Epub 2005 Feb 8.
Keywords
AgedAphasia/etiology/*pathologyCerebral AngiographyCerebral Cortex/pathologyCerebral Infarction/complications/*pathologyCorpus Striatum/pathologyFemaleHumansInternal Capsule/pathologyMaleMiddle AgedTelencephalon/*pathologyDiffusion Magnetic Resonance Imaging
Abstract
BACKGROUND: The underlying mechanism of aphasia following striatocapsular infarction (SCI) remains controversial. We hypothesized that aphasia resulting from SCI might be associated with concomitant cortical lesions, which can be demonstrated by diffusion-weighted imaging (DWI). METHODS: We analyzed 24 patients with left SCI who underwent DWI and MR angiography within 2 days after the onset. Aphasia was assessed by the modified Korean version of the Boston Diagnostic Aphasia Examination test. RESULTS: DWI showed the presence of additional ischemic lesions involving the cortical areas in 13 of 24 SCI patients (54%). Ten patients (42%) showed aphasia. All 10 patients with aphasia had cortical lesions in addition to SCI (p = 0.0002), whereas 21% (3/14) of the nonaphasic patients had additional cortical lesions. Conventional MRI did not reveal the presence of corresponding acute cortical lesions in any of the aphasic patients. There was no difference between the patients with and without aphasia in terms of their stroke etiology. CONCLUSIONS: Our data suggest that aphasia due to SCI in the acute stage may be attributed to direct cortical injury, whose presence can be demonstrated by DWI, even though it might be invisible on conventional imaging.
ISSN
1015-9770 (Print)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15703465

https://hdl.handle.net/10371/16042
DOI
https://doi.org/10.1159/000083886
Files in This Item:
There are no files associated with this item.
Appears in Collections:

Altmetrics

Item View & Download Count

  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Share