S-Space College of Engineering/Engineering Practice School (공과대학/대학원) Dept. of Computer Science and Engineering (컴퓨터공학부) Journal Papers (저널논문_컴퓨터공학부)
The use of gold nanoparticle aggregation for DNA computing and logic-based biomolecular detection
- Lee, In-Hee; Yang, Kyung-Ae; Lee, Ji-Hoon; Park, Ji-Yoon; Chai, Young Kyu; Lee, Jae-Hoon; Zhang, Byoung-Tak
- Issue Date
- Institute of Physics
- Nanotechnology 19 395103
- The use of DNA molecules as a physical computational material has attracted much interest, especially in the area of DNA computing. DNAs are also useful for logical control and analysis of biological systems if efficient visualization methods are available. Here we present a quick
and simple visualization technique that displays the results of the DNA computing process based on a colorimetric change induced by gold nanoparticle aggregation, and we apply it to the logic-based detection of biomolecules. Our results demonstrate its effectiveness in both DNA-based logical computation and logic-based biomolecular detection.