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The comparison of the impact of arterial stiffness and central pressure on left ventricular geometry and diastolic function
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Hack-Lyoung | - |
dc.contributor.author | Lim, Woo-Hyun | - |
dc.contributor.author | Seo, Jae-Bin | - |
dc.contributor.author | Kim, Sang-Hyun | - |
dc.contributor.author | Zo, Zoo-Hee | - |
dc.contributor.author | Kim, Myung-A | - |
dc.date.accessioned | 2019-11-07T01:04:26Z | - |
dc.date.available | 2019-11-07T10:05:16Z | - |
dc.date.issued | 2019-09-01 | - |
dc.identifier.citation | Clinical Hypertension, 25(1):18 | ko_KR |
dc.identifier.issn | 2056-5909 | - |
dc.identifier.uri | https://hdl.handle.net/10371/162634 | - |
dc.description.abstract | Background
This study was performed to compare the associations of brachial-ankle pulse wave velocity (baPWV) and central blood pressure (CBP) measurements with left ventricular (LV) geometry and diastolic function. Methods A total of 77 subjects (64.5 ± 10.8 years, 67.5% females) without documented cardiovascular disease were prospectively recruited. All subjects underwent transthoracic echocardiography, baPWV and noninvasive measurement of CBP on the same day. Results In simple linear correlation analyses, neither baPWV nor CBP was associated with LV mass index or relative wall thickness (P > 0.05 for each). Although baPWV significantly correlated with septal e´ velocity in simple linear correlation analyses (r = 0.258, P = 0.025), the significance was lost after controlling for potential confounder (P = 0.881). In simple linear correlation analyses, central systolic blood pressure (CSBP) and central pulse pressure (CPP) significantly correlated with both septal e´ velocity or E/e´ (P < 0.05 for each); however, neither central diastolic nor mean arterial pressures was associated with both septal e´ velocity and E/e´ (P > 0.05 for each). After controlling for confounders, including age, sex and body mass index, CSBP correlated with septal e´ velocity (β = − 0.258, P = 0.025), but not with E/e´ (P = 0.074). CPP correlated with both septal e´ velocity (β = − 0.300, P = 0.014) and E/e´ (β = 0.428, P = 0.002) in the same multivariable model. Conclusions In subjects without documented cardiovascular disease, CSBP and CPP may be more strongly associated with LV diastolic function than baPWV. Further studies with a larger sample size are needed to confirm our results. | ko_KR |
dc.description.sponsorship | This study was supported by a research grant from the Korean Society of Hypertension. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | BioMed Central | ko_KR |
dc.subject | Arterial stiffness | ko_KR |
dc.subject | Central blood pressure | ko_KR |
dc.subject | Diastolic function | ko_KR |
dc.subject | Left ventricle | ko_KR |
dc.subject | Morphology | ko_KR |
dc.title | The comparison of the impact of arterial stiffness and central pressure on left ventricular geometry and diastolic function | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 김학령 | - |
dc.contributor.AlternativeAuthor | 임우현 | - |
dc.contributor.AlternativeAuthor | 서재빈 | - |
dc.contributor.AlternativeAuthor | 김상현 | - |
dc.contributor.AlternativeAuthor | 조주희 | - |
dc.contributor.AlternativeAuthor | 김명아 | - |
dc.identifier.doi | 10.1186/s40885-019-0125-9 | - |
dc.language.rfc3066 | en | - |
dc.rights.holder | The Author(s). | - |
dc.date.updated | 2019-09-01T03:56:51Z | - |
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