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Clinical outcomes of radiation-based locoregional therapy in locally advanced head and neck squamous cell carcinoma patients not responding to induction chemotherapy
DC Field | Value | Language |
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dc.contributor.author | Lim, Yoojoo | - |
dc.contributor.author | Keam, Bhumsuk | - |
dc.contributor.author | Koh, Youngil | - |
dc.contributor.author | Kim, Tae Min | - |
dc.contributor.author | Lee, Se-Hoon | - |
dc.contributor.author | Hah, J. Hun | - |
dc.contributor.author | Kwon, Tack-Kyun | - |
dc.contributor.author | Kim, Dong-Wan | - |
dc.contributor.author | Wu, Hong-Gyun | - |
dc.contributor.author | Sung, Myung-Whun | - |
dc.contributor.author | Heo, Dae Seog | - |
dc.contributor.author | Kim, Kwang Hyun | - |
dc.date.accessioned | 2020-04-27T11:29:41Z | - |
dc.date.available | 2020-04-27T11:29:41Z | - |
dc.date.created | 2020-02-19 | - |
dc.date.issued | 2013-07 | - |
dc.identifier.citation | Oral Surgery Oral Medicine Oral Pathology Oral Radiology, Vol.116 No.1, pp.55-60 | - |
dc.identifier.issn | 2212-4403 | - |
dc.identifier.other | 91789 | - |
dc.identifier.uri | https://hdl.handle.net/10371/165460 | - |
dc.description.abstract | Objective. The purpose of this study was to evaluate the efficacy of radiation-based locoregional therapy for locally advanced head and neck squamous cell carcinoma (LA-HNSCC) patients who did not respond to induction chemotherapy (IC). Study Design. Outcomes after radiation-based locoregional therapy were retrospectively analyzed. Results. Among a total of 208 patients treated with IC, 46 (22.1%) did not respond. After IC, patients were treated with radiotherapy (RT), concurrent chemoradiotherapy (CCRT), or surgery with or without postoperative RT. Among the 46 nonresponders, 17 (37.8%) patients underwent surgery and 28 (62.2%) were treated with RT or CCRT. Responses to subsequent RT or CCRT for 26 evaluable patients were as follows: complete response = 7 (26.9%), partial response = 9 (34.6%), stable disease = 4 (15.4%), and progressive disease = 6 (23.1%). Conclusion. A significant proportion of LA-HNSCC patients who did not respond to IC can benefit from subsequent RT or CCRT. | - |
dc.language | 영어 | - |
dc.publisher | Elsevier USA | - |
dc.title | Clinical outcomes of radiation-based locoregional therapy in locally advanced head and neck squamous cell carcinoma patients not responding to induction chemotherapy | - |
dc.type | Article | - |
dc.contributor.AlternativeAuthor | 우홍균 | - |
dc.contributor.AlternativeAuthor | 허대석 | - |
dc.contributor.AlternativeAuthor | 성명훈 | - |
dc.contributor.AlternativeAuthor | 김광현 | - |
dc.contributor.AlternativeAuthor | 권택균 | - |
dc.contributor.AlternativeAuthor | 김동완 | - |
dc.identifier.doi | 10.1016/j.oooo.2013.02.007 | - |
dc.citation.journaltitle | Oral Surgery Oral Medicine Oral Pathology Oral Radiology | - |
dc.identifier.wosid | 000320369200022 | - |
dc.identifier.scopusid | 2-s2.0-84879110471 | - |
dc.citation.endpage | 60 | - |
dc.citation.number | 1 | - |
dc.citation.startpage | 55 | - |
dc.citation.volume | 116 | - |
dc.identifier.sci | 000320369200022 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Kwon, Tack-Kyun | - |
dc.contributor.affiliatedAuthor | Kim, Dong-Wan | - |
dc.contributor.affiliatedAuthor | Wu, Hong-Gyun | - |
dc.contributor.affiliatedAuthor | Sung, Myung-Whun | - |
dc.contributor.affiliatedAuthor | Heo, Dae Seog | - |
dc.contributor.affiliatedAuthor | Kim, Kwang Hyun | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | ADVANCED LARYNGEAL-CANCER | - |
dc.subject.keywordPlus | ORGAN PRESERVATION | - |
dc.subject.keywordPlus | PHASE-III | - |
dc.subject.keywordPlus | FLUOROURACIL | - |
dc.subject.keywordPlus | RADIOTHERAPY | - |
dc.subject.keywordPlus | CISPLATIN | - |
dc.subject.keywordPlus | CHEMOSENSITIVITY | - |
dc.subject.keywordPlus | DOCETAXEL | - |
dc.subject.keywordPlus | SURVIVAL | - |
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