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Precision genome engineering through adenine and cytosine base editing
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Jin-Soo | - |
dc.date.accessioned | 2020-04-27T13:01:41Z | - |
dc.date.available | 2020-04-27T13:01:41Z | - |
dc.date.created | 2019-07-24 | - |
dc.date.created | 2019-07-24 | - |
dc.date.issued | 2018-03 | - |
dc.identifier.citation | Nature Plants, Vol.4 No.3, pp.148-151 | - |
dc.identifier.issn | 2055-026X | - |
dc.identifier.other | 79555 | - |
dc.identifier.uri | https://hdl.handle.net/10371/165709 | - |
dc.description.abstract | Adenine base editors (ABEs), composed of an engineered deaminase and a catalytically impaired CRISPR-Cas9 variant, are powerful new tools for targeted base editing in cells and organisms. Together with cytosine base editors (CBEs), ABEs enable single-nucleotide conversions cleanly, efficiently and reversibly without double-stranded DNA cleavage, advancing genome editing in a new dimension. | - |
dc.language | 영어 | - |
dc.publisher | Palgrave Macmillan Ltd. | - |
dc.title | Precision genome engineering through adenine and cytosine base editing | - |
dc.type | Article | - |
dc.contributor.AlternativeAuthor | 김진수 | - |
dc.identifier.doi | 10.1038/s41477-018-0115-z | - |
dc.citation.journaltitle | Nature Plants | - |
dc.identifier.wosid | 000428810500009 | - |
dc.identifier.scopusid | 2-s2.0-85042525786 | - |
dc.citation.endpage | 151 | - |
dc.citation.number | 3 | - |
dc.citation.startpage | 148 | - |
dc.citation.volume | 4 | - |
dc.identifier.sci | 000428810500009 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Kim, Jin-Soo | - |
dc.type.docType | Review | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | DEAMINASE FUSION | - |
dc.subject.keywordPlus | MAMMALIAN-CELLS | - |
dc.subject.keywordPlus | DNA CLEAVAGE | - |
dc.subject.keywordPlus | CRISPR-CAS9 | - |
dc.subject.keywordPlus | NUCLEASES | - |
dc.subject.keywordPlus | RIBONUCLEOPROTEINS | - |
dc.subject.keywordPlus | INVERSIONS | - |
dc.subject.keywordPlus | EMBRYOS | - |
dc.subject.keywordPlus | RICE | - |
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