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Deep-sea hydrothermal vent bacteria related to human pathogenic Vibrio species

Cited 22 time in Web of Science Cited 22 time in Scopus
Authors
Hasan, Nur A.; Grim, Christopher J.; Lipp, Erin K.; Rivera, Irma N. G.; Chun, Jongsik; Haley, Bradd J.; Taviani, Elisa; Choi, Seon Young; Hoq, Mozammel; Munk, A. Christine; Brettin, Thomas S.; Bruce, David; Challacombe, Jean F.; Detter, J. Chris; Han, Cliff S.; Eisen, Jonathan A.; Huq, Anwar; Colwell, Rita R.
Issue Date
2015-05
Citation
Proceedings of the National Academy of Sciences of the United States of America, Vol.112 No.21, pp.E2813-E2819
Keywords
Vibriohydrothermal ventgenomicsEX25
Abstract
Vibrio species are both ubiquitous and abundant in marine coastal waters, estuaries, ocean sediment, and aquaculture settings world-wide. We report here the isolation, characterization, and genome sequence of a novel Vibrio species, Vibrio antiquarius, isolated from a mesophilic bacterial community associated with hydrothermal vents located along the East Pacific Rise, near the southwest coast of Mexico. Genomic and phenotypic analysis revealed V. antiquarius is closely related to pathogenic Vibrio species, namely Vibrio alginolyticus, Vibrio parahaemolyticus, Vibrio harveyi, and Vibrio vulnificus, but sufficiently divergent to warrant a separate species status. The V. antiquarius genome encodes genes and operons with ecological functions relevant to the environment conditions of the deep sea and also harbors factors known to be involved in human disease caused by freshwater, coastal, and brackish water vibrios. The presence of virulence factors in this deep-sea Vibrio species suggests a far more fundamental role of these factors for their bacterial host. Comparative genomics revealed a variety of genomic events that may have provided an important driving force in V. antiquarius evolution, facilitating response to environmental conditions of the deep sea.
ISSN
0027-8424
URI
http://hdl.handle.net/10371/165759
DOI
https://doi.org/10.1073/pnas.1503928112
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College of Natural Sciences (자연과학대학)Dept. of Biological Sciences (생명과학부)Journal Papers (저널논문_생명과학부)
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