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MeCP2 Caught Moonlighting as a Suppressor of MicroRNA Processing

Cited 7 time in Web of Science Cited 7 time in Scopus
Authors
Woo, Jae-Sung; Kim, V. Narry
Issue Date
2014-03
Citation
Developmental Cell, Vol.28 No.5, pp.477-478
Abstract
MeCP2 is a transcriptional regulator important for neurodevelopment and is involved in Rett syndrome and autism. In this issue of Developmental Cell, Cheng and colleagues (2014) report that MeCP2 also regulates microRNA biogenesis. MeCP2 phosphorylation induces a direct interaction with DGCR8, leading to reduced microRNA processing and retardation of dendritic growth.
ISSN
1534-5807
URI
https://hdl.handle.net/10371/171912
DOI
https://doi.org/10.1016/j.devcel.2014.02.015
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College of Natural Sciences (자연과학대학)Dept. of Biological Sciences (생명과학부)Journal Papers (저널논문_생명과학부)
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