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MeCP2 Caught Moonlighting as a Suppressor of MicroRNA Processing
Cited 8 time in
Web of Science
Cited 8 time in Scopus
- Authors
- Issue Date
- 2014-03
- Publisher
- Cell Press
- Citation
- Developmental Cell, Vol.28 No.5, pp.477-478
- Abstract
- MeCP2 is a transcriptional regulator important for neurodevelopment and is involved in Rett syndrome and autism. In this issue of Developmental Cell, Cheng and colleagues (2014) report that MeCP2 also regulates microRNA biogenesis. MeCP2 phosphorylation induces a direct interaction with DGCR8, leading to reduced microRNA processing and retardation of dendritic growth.
- ISSN
- 1534-5807
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Related Researcher
- College of Natural Sciences
- School of Biological Sciences
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