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An Arabidopsis homologue of human seven-in-absentia-interacting protein is involved in pathogen resistance

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Authors
Kim, Youn-Sung; Ham, Byung-Kook; Paek, Kyung-Hee; Park, Chung-Mo; Chua, Nam-Hai
Issue Date
2006-06
Citation
Molecules and Cells, Vol.21 No.3, pp.389-394
Keywords
Arabidopsis thalianabiotic stressdisease resistancehydrogen peroxideSIAH interacting proteinwounding
Abstract
Human seven-in-absentia (SIAH)-interacting protein (SIP) is a component of the E3 ligase complex targeting beta-catenin for destruction. Arabidopsis has one SIP protein (AtSIP) with 32% amino acid sequence identity to SIP. To investigate the functions of AtSIP, we isolated an atsip knockout mutant, and generated transgenic plants overexpressing AtSIP. The growth rates and morphologies of the atsip and transgenic plants were indistinguishable from those of wild type. However, atsip plants were more susceptible to Pseudomonas syringae infection, and the transgenic plants overexpressing AtSIP were more resistant. Consistent with this, RNA blot analysis showed that the AtSIP gene is strongly induced by wounding and hydrogen peroxide treatment. In addition, when plants were infected with P. syringae, AtSIP was transiently induced prior to PR-1 induction. These observations show that Arabidopsis AtSIP plays a role in resistance to pathogenic infection.
ISSN
1016-8478
URI
https://hdl.handle.net/10371/172009
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College of Natural Sciences (자연과학대학)Dept. of Chemistry (화학부)Journal Papers (저널논문_화학부)
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