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High-level secretion of a virally encoded anti-fungal toxin in transgenic tobacco plants

Cited 23 time in Web of Science Cited 26 time in Scopus
Authors
Park, Chung-Mo; Berry, JO; Bruenn, JA
Issue Date
1996-01
Citation
Plant Molecular Biology, Vol.30 No.2, pp.359-366
Keywords
anti-fungal killer toxindouble-stranded RNAgene expressiontransgenic plantUstilago maydis
Abstract
Ustilago maydis killer toxins are small polypeptides (7-14 kDa) which kill susceptible cells of closely related fungal species. The KP4 toxin is a single polypeptide subunit with a molecular weight of 11.1 kDa. In this work, a transgenic tobacco plant was constructed which secretes the KP4 toxin at a high level. The KP4 toxin expressed in this transgenic plant was of the same size and specificity as the authentic Ustilago KP4 toxin. The expression level was at least 500 times higher than that of the KP6 toxin expressed in plants. Transgenic crop plants producing the KP4 toxin could be rendered resistant to KP4-susceptible fungal pathogens.
ISSN
0167-4412
URI
https://hdl.handle.net/10371/172050
DOI
https://doi.org/10.1007/BF00020122
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College of Natural Sciences (자연과학대학)Dept. of Chemistry (화학부)Journal Papers (저널논문_화학부)
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