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A second double-stranded RNA virus from yeast

Cited 34 time in Web of Science Cited 36 time in Scopus
Authors
Park, Chung-Mo; Lopinski, JD; Masuda, J; Tzeng, TH; Bruenn, JA
Issue Date
1996-02
Citation
Virology, Vol.216 No.2, pp.451-454
Abstract
Two double-stranded RNA viruses exist as permanent persistent infections of the yeast Saccharomyces cerevisiae: ScVL1 and ScVLa. Both belong to the Totiviridae, which include a number of fungal and protozoan double-stranded RNA viruses. Although ScVL1 and ScVLa share the same genomic organization and mode of expression and coexist in the same cells, they show no evidence of recombination: with one limited exception, sequence conservation is detectable only in regions conserved in all totiviruses. Both have two open reading frames on their single essential RNAs: cap (encoding a capsid polypeptide) and pol (encoding an RNA-dependent RNA polymerase). The ScVLa virus, like ScVL1, appears to express its Pol domain by a -1 translational frameshift. (C) 1996 Academic Press, Inc.
ISSN
0042-6822
URI
https://hdl.handle.net/10371/172101
DOI
https://doi.org/10.1006/viro.1996.0083
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College of Natural Sciences (자연과학대학)Dept. of Chemistry (화학부)Journal Papers (저널논문_화학부)
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