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Biodegradable Nano-Polymeric System for Efficient Akt1 siRNA Delivery

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dc.contributor.authorJere, Dhananjay-
dc.contributor.authorArote, Rohidas-
dc.contributor.authorJiang, Hu-Lin-
dc.contributor.authorKim, You-Kyoung-
dc.contributor.authorCho, Myung-Haing-
dc.contributor.authorCho, Chong-Su-
dc.date.accessioned2021-01-31T08:46:19Z-
dc.date.available2021-01-31T08:46:19Z-
dc.date.created2018-01-19-
dc.date.created2018-01-19-
dc.date.issued2010-05-
dc.identifier.citationJournal of Nanoscience and Nanotechnology, Vol.10 No.5, pp.3366-3369-
dc.identifier.issn1533-4880-
dc.identifier.other24916-
dc.identifier.urihttps://hdl.handle.net/10371/172440-
dc.description.abstractBiodegradable nano-polymeric carrier composed of polycaprolactone (PCL) and polyethylenimine (PEI) (BNPP) was successfully synthesized for the delivery of sh/siRNA in lung cancer cells. BNPP efficiently and safely delivered siRNA in lung cancer cells. BNPP-delivered Akt1 siRNA silenced Akt1 protein, and reduced the cancer cell survival, proliferation, malignancy and metastasis.-
dc.language영어-
dc.publisherAmerican Scientific Publishers-
dc.titleBiodegradable Nano-Polymeric System for Efficient Akt1 siRNA Delivery-
dc.typeArticle-
dc.contributor.AlternativeAuthor조명행-
dc.identifier.doi10.1166/jnn.2010.2228-
dc.citation.journaltitleJournal of Nanoscience and Nanotechnology-
dc.identifier.wosid000275626200074-
dc.identifier.scopusid2-s2.0-77952507261-
dc.citation.endpage3369-
dc.citation.number5-
dc.citation.startpage3366-
dc.citation.volume10-
dc.identifier.sci000275626200074-
dc.description.isOpenAccessN-
dc.contributor.affiliatedAuthorArote, Rohidas-
dc.contributor.affiliatedAuthorCho, Myung-Haing-
dc.contributor.affiliatedAuthorCho, Chong-Su-
dc.type.docTypeArticle; Proceedings Paper-
dc.description.journalClass1-
dc.subject.keywordPlusLUNG-CANCER CELLS-
dc.subject.keywordPlusGENE CARRIER-
dc.subject.keywordAuthorsiRNA Delivery-
dc.subject.keywordAuthorNonviral Vectors-
dc.subject.keywordAuthorPolycaprolactone-
dc.subject.keywordAuthorPolymeric Carrier-
dc.subject.keywordAuthorLung Cancer-
dc.subject.keywordAuthorAkt1 Protein-
dc.subject.keywordAuthorNanocarriers-
dc.subject.keywordAuthorGene Delivery-
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  • College of Veterinary Medicine
  • Department of Veterinary Medicine
Research Area Nanotoxicology, Veterinary Toxicology

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