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Antioxidative effects of 7-hydroxy-3-methoxy-cadalene extracted from Zelkova serrata on 4-(methylinitros amino) 1-(3-pyridyl)-1-butanone-induced oxidative stress in A/J mice
DC Field | Value | Language |
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dc.contributor.author | Kim, JH | - |
dc.contributor.author | Lee, HJ | - |
dc.contributor.author | Yeon, SC | - |
dc.contributor.author | Choi, DH | - |
dc.contributor.author | Lee, SS | - |
dc.contributor.author | Kang, JK | - |
dc.contributor.author | Chae, CH | - |
dc.contributor.author | Paik, NW | - |
dc.contributor.author | Lee, KH | - |
dc.contributor.author | Cho, MH | - |
dc.date.accessioned | 2021-01-31T08:49:25Z | - |
dc.date.available | 2021-01-31T08:49:25Z | - |
dc.date.created | 2018-04-11 | - |
dc.date.issued | 2004-05 | - |
dc.identifier.citation | Phytotherapy Research, Vol.18 No.5, pp.425-427 | - |
dc.identifier.issn | 0951-418X | - |
dc.identifier.other | 31943 | - |
dc.identifier.uri | https://hdl.handle.net/10371/172497 | - |
dc.description.abstract | Effects of 7-hydroxy-3-methoxy-cadalene (cadalene) extracted from Zelkova serrata on 4-(methylinitrosamino)1-(3-pyridyl)-1-butanone (NNK)-induced oxidative stress were examined using A/J mice. NNK (65 mug/ml water) was orally administered to 20 mice for 7 weeks, followed by free feeding of a commercial diet, not containing cadalene, for 2 weeks. The control group was maintained without NNK and cadalene administration, and treatment groups with NNK and cadalene (6.25, 25, 100 mg/kg feed) feeding for 25 weeks. The glutathione concentration of cadalene-treated (65 mug/ml water) group was significantly higher than that of the group treated only with NNK (p < 0.05). The results of our study strongly indicate that cadalene exerts antioxidative effect on NNK-induced lung tumorigenesis in A/J mice. Copyright (C) 2004 John Wiley Sons, Ltd. | - |
dc.language | 영어 | - |
dc.publisher | John Wiley & Sons Inc. | - |
dc.title | Antioxidative effects of 7-hydroxy-3-methoxy-cadalene extracted from Zelkova serrata on 4-(methylinitros amino) 1-(3-pyridyl)-1-butanone-induced oxidative stress in A/J mice | - |
dc.type | Article | - |
dc.contributor.AlternativeAuthor | 조명행 | - |
dc.identifier.doi | 10.1002/ptr.1427 | - |
dc.citation.journaltitle | Phytotherapy Research | - |
dc.identifier.wosid | 000221802400016 | - |
dc.identifier.scopusid | 2-s2.0-2942565871 | - |
dc.citation.endpage | 427 | - |
dc.citation.number | 5 | - |
dc.citation.startpage | 425 | - |
dc.citation.volume | 18 | - |
dc.identifier.sci | 000221802400016 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Chae, CH | - |
dc.contributor.affiliatedAuthor | Paik, NW | - |
dc.contributor.affiliatedAuthor | Cho, MH | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | PERFORMANCE LIQUID-CHROMATOGRAPHY | - |
dc.subject.keywordPlus | GLUTATHIONE | - |
dc.subject.keywordAuthor | 7-hydroxy-3-methoxy-caclalene | - |
dc.subject.keywordAuthor | 4-(methylinitrosamino)-1-(3-pyridyl)-1-butanone gultathione | - |
dc.subject.keywordAuthor | antioxidant | - |
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