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Specific targeting, cell sorting, and bioimaging with smart magnetic silica core-shell nanomateriats

Cited 257 time in Web of Science Cited 268 time in Scopus
Authors
Yoon, Tae‐Jong; Yu, Kyeong Nam; Kim, Eunha; Kim, Jun Sung; Kim, Byung Geol; Yun, Sang‐Hyun; Sohn, Byeong‐Hyeok; Cho, Myung‐Haing; Lee, Jin‐Kyu; Park, Seung Bum
Issue Date
2006-02
Citation
Small, Vol.2 No.2, pp.209-215
Keywords
bioimagingcell recognitioncore-shell materialsmagnetic propertiesnanobiotechnology
Abstract
The scope of smart magnetic silica core-shell nanomaterials in specific targeting, cell sorting, and bioimaging was demonstrated. In the study the silica shell of the MNP@SiO2 incorporated with commonly used dyes were modified with various functional organosilicon compounds. The surface of the dual-functionalized core-shell nanoparticles presented two key functional groups - PEG moiety and amine moiety. The MNP@SiO2 exhibited the specific recognition of floating tumor cells.
ISSN
1613-6810
URI
https://hdl.handle.net/10371/172509
DOI
https://doi.org/10.1002/smll.200500360
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College of Veterinary Medicine (수의과대학)Dept. of Veterinary Medicine (수의학과)Journal Papers (저널논문_수의학과)
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