Browse

Transcription factors and mitogen-activated protein kinases as molecular targets for chemoprevention with anti-inflammatory phytochemicals

Cited 13 time in Web of Science Cited 13 time in Scopus
Authors
Surh, Young‐Joon; Na, Hye‐Kyung; Lee, Seung Sei
Issue Date
2004
Citation
BioFactors, Vol.21 No.1-4, pp.103-108
Keywords
cyclooxygenase-2chemopreventionNF-kappa BMAP kinasesphytochemicals
Abstract
Chemoprevention refers to the use of nontoxic chemical substances to inhibit, reverse, or retard tumorigenesis. Numerous compounds derived from edible plants have been reported to interfere with a specific stage of the carcinogenic process. Some anti-inflammatory phytochemicals with cyclooxygenase-2 inhibitory activity have been found to exert chemopreventive properties by targeting intracellular signaling molecules (recently reviewed by Y.J. Surh, Nature Reviews Cancer, 3: 768-780, 2003). These include mitogen-activated protein kinases and transcription factors, such as NF-kappaB and AP-1.
ISSN
0951-6433
URI
https://hdl.handle.net/10371/172633
DOI
https://doi.org/10.1002/biof.552210119
Files in This Item:
There are no files associated with this item.
Appears in Collections:
Graduate School of Convergence Science and Technology (융합과학기술대학원)Dept. of Molecular and Biopharmaceutical Sciences (분자의학 및 바이오제약학과)Journal Papers (저널논문_분자의학 및 바이오제약학과)
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse