Browse

Inhibition of cyclooxygenase-2 expression by diarylheptanoids from the bark of Alnus hirsuta var. sibirica

Cited 0 time in Web of Science Cited 57 time in Scopus
Authors
Lee, Min-Won; Kim, Jung-Hwan; Jeong, Dong-Wook; Ahn, Kyoung-Hwan; Toh, Sang-Hak; Surh, Young-Joon
Issue Date
2000-04
Citation
Biological and Pharmaceutical Bulletin, Vol.23 No.4, pp.517-518
Keywords
Alnus hirsuta var. sibiricacyclooxygenase-2 inhibitordiarylheptanoid
Abstract
Two known diarylheptanoids, oregonin (1), (5S)-1,7-bis-(3,4-dihydroxyphenyl)-heptane-3-one-5-O-beta-D-xylopyranoside and hirsutanonol (2), (5S)-1,7-bis-(3,4-dihydrosxphenyl)-5-hydroxyheptane-3-one isolated from the bark of Alnus hirsuta var. sibirica, showed significant inhibitory effects on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced cyclooxygenase-2 (COX-2) expression in immortalized human breast epithelial MCF10A cells.
ISSN
0918-6158
URI
https://hdl.handle.net/10371/172640
DOI
https://doi.org/10.1248/bpb.23.517
Files in This Item:
There are no files associated with this item.
Appears in Collections:
Graduate School of Convergence Science and Technology (융합과학기술대학원)Dept. of Molecular and Biopharmaceutical Sciences (분자의학 및 바이오제약학과)Journal Papers (저널논문_분자의학 및 바이오제약학과)
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse