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Ginger-derived phenolic substances with cancer preventive and therapeutic potential

Cited 65 time in Web of Science Cited 73 time in Scopus
Authors
Kundu, Joydeb Kumar; Na, Hye-Kyung; Surh, Young-Joon
Issue Date
2009
Citation
Forum of Nutrition, Vol.61, pp.182-192
Abstract
Ginger, the rhizomes of Zingiber officinale Roscoe (Zingiberaceae), has widely been used as a spice and condiment in different societies. Besides its food-additive functions, ginger has a long history of medicinal use for the treatment of a variety of human ailments including common colds, fever, rheumatic disorders, gastrointestinal complications, motion sickness, diabetes, cancer, etc. Ginger contains several nonvolatile pungent principles viz. gingerols, shogaols, paradols and zingerone, which account for many of its health beneficial effects. Studies conducted in cultured cells as well as in experimental animals revealed that these pungent phenolics possess anticarcinogenic properties. This chapter summarizes updated information on chemopreventive and chemotherapeutic effects of ginger-derived phenolic substances and their underlying mechanisms. Copyright (C) 2009 S. Karger AG, Basel
ISSN
1660-0347
URI
https://hdl.handle.net/10371/172712
DOI
https://doi.org/10.1159/000212750
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Graduate School of Convergence Science and Technology (융합과학기술대학원)Dept. of Molecular and Biopharmaceutical Sciences (분자의학 및 바이오제약학과)Journal Papers (저널논문_분자의학 및 바이오제약학과)
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