Publications
Detailed Information
Increased MAPK activity and MKP-1 overexpression in human gastric adenocarcinoma
Cited 93 time in
Web of Science
Cited 100 time in Scopus
- Authors
- Issue Date
- 1998-09
- Publisher
- Academic Press
- Citation
- Biochemical and Biophysical Research Communications, Vol.250 No.1, pp.43-47
- Abstract
- Mitogen-activated protein kinase (MAPK) has been known to play a critical role in the regulation of the carcinogenesis in human cancers. In an effort to understand the functional role of the MAPK in the carcinogenesis of human gastric tissues, we examined the changes of MAPK levels in human gastric adenocarcinoma, We found that increased MAPK activity was accompanied by overexpression of mitogen-activated protein kinase phosphatase-l (MKP-1), suggesting that signaling pathways leading to the activation of MAPK and the induction of MKP-1 expression are associated with carcinogenesis of human gastric adenocarcinoma, (C) 1998 Academic Press.
- ISSN
- 0006-291X
- Files in This Item:
- There are no files associated with this item.
- Appears in Collections:
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.